SCHEMBL18692002

SCHEMBL18692002

C[Si](C)(O)c1ccccc1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.45
CA2 P00918 4/20 0.45
TDP1 Q9NUW8 3/20 0.45
ALOX15 P16050 3/20 0.45
LMNA P02545 3/20 0.45
NPC1 O15118 3/20 0.45
HPGD P15428 3/20 0.45
HSD17B10 Q99714 3/20 0.45
CA4 P22748 2/20 0.45
EGFR P00533 2/20 0.45
FYN P06241 2/20 0.45
MMP9 P14780 2/20 0.45
RECQL P46063 2/20 0.45
KDM4E B2RXH2 2/20 0.45
MAPT P10636 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
CA12 O43570 1/20 0.45
GMNN O75496 1/20 0.45
POLB P06746 1/20 0.45
CA3 P07451 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3209059 0.83 ESR1 (0.35) ALDH1A1CA2TDP1ALOX15LMNA
SCHEMBL10340777 0.81 ALDH1A1 (0.47) ALDH1A1CA2TDP1ALOX15LMNA
SCHEMBL78717 0.81 ALDH1A1 (0.47) ALDH1A1CA2TDP1ALOX15LMNA
SCHEMBL3362043 0.75 LMNA (0.41) ALDH1A1CA2TDP1ALOX15LMNA
SCHEMBL2543212 0.75 ALDH1A1 (0.53) ALDH1A1CA2TDP1ALOX15LMNA
SCHEMBL23701311 0.73 CA2 (0.48) ALDH1A1CA2TDP1ALOX15LMNA
SCHEMBL18796464 0.73 CA2 (0.39) ALDH1A1CA2TDP1ALOX15LMNA
SCHEMBL18796080 0.73 GABRA1 (0.43) ALDH1A1CA2TDP1ALOX15LMNA
SCHEMBL23701057 0.73 CA2 (0.43) ALDH1A1CA2TDP1ALOX15LMNA
SCHEMBL18796166 0.73 ALDH1A1 (0.43) ALDH1A1CA2TDP1ALOX15LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10723845-B2 Process for preparing linear carbosiloxane polymers DOW SILICONES CORPORATION (US) 2020-07-28 US disclosed
US-20200079911-A1 PROCESS FOR PREPARING LINEAR CARBOSILOXANE POLYMERS DOW CORNING EUROPE S.A. 2020-03-12 US disclosed
EP-3153540-B1 PROCESS FOR PREPARING LINEAR CARBOSILOXANE POLYMERS DOW CORNING (US) 2018-06-06 EP disclosed
WO-2017062091-A1 PROCESS FOR PREPARING LINEAR CARBOSILOXANE POLYMERS DOW CORNING CORPORATION (US) 2017-04-13 WO disclosed
EP-3153540-A1 PROCESS FOR PREPARING LINEAR CARBOSILOXANE POLYMERS Dow Corning Corporation (US) 2017-04-12 EP disclosed