Uridine_Diphosphate

Uridine_Diphosphate

SCHEMBL1873401

O=c1ccn([C@@H]2O[C@H](COP(=O)([O-])OP(=O)([O-])O)[C@@H](O)[C@H]2O)c(=O)[nH]1.[Na+].[Na+]

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Uridine_Diphosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ P2RY2 known ✓ P41231 13/20 0.88
▸ P2RY6 known ✓ Q15077 9/20 0.88
▸ P2RY4 known ✓ P51582 7/20 0.88
▸ P2RY14 Q15391 6/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Uridine Triphosphate SCHEMBL29764233 0.98 P2RY2 (0.92) P2RY2P2RY6P2RY4P2RY14
Uridine Triphosphate SCHEMBL1230651 0.98 P2RY2 (0.92) P2RY2P2RY6P2RY4P2RY14
SCHEMBL4149994 0.98 P2RY2 (0.92) P2RY2P2RY6P2RY4P2RY14
Uridine Triphosphate SCHEMBL27196289 0.97 P2RY2 (0.90) P2RY2P2RY6P2RY4P2RY14
Uridine Triphosphate SCHEMBL317396 0.97 P2RY2 (0.90) P2RY2P2RY6P2RY4P2RY14
Uridine_Diphosphate SCHEMBL1321688 0.94 P2RY2 (0.92) P2RY2P2RY6P2RY4P2RY14
Diquafosol SCHEMBL1651092 0.94 P2RY2 (1.00) P2RY2P2RY6P2RY4P2RY14
Uridine_Diphosphate SCHEMBL23534623 0.93 P2RY2 (0.90) P2RY2P2RY6P2RY4P2RY14
Uridine_Diphosphate SCHEMBL31501785 0.93 P2RY2 (0.90) P2RY2P2RY6P2RY4P2RY14
SCHEMBL28484030 0.92 P2RY2 (0.82) P2RY2P2RY6P2RY4P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120060187-A Immobilized enzyme composition and application thereof in efficient preparation of rebaudioside M 成都圆大生物科技有限公司 2025-05-30 — — CN claimed
CN-120005924-A Method for synthesizing rebaudioside M by utilizing enzyme cascade reaction 江苏大学 2025-05-16 — — CN claimed
CN-118207275-A Method for producing rebaudioside D and D-psicose by one-pot method 万华化学集团股份有限公司 2024-06-18 — — CN claimed
CN-118165949-A Co-immobilized enzyme and preparation method and application thereof 万华化学集团股份有限公司 2024-06-11 — — CN claimed
CN-118147258-A Method for recycling disodium uridine diphosphate and application thereof 万华化学集团股份有限公司 2024-06-07 — — CN claimed
CN-116478228-A Uridine diphosphate metal complex, preparation method and application thereof 北京理工大学 2023-07-25 — — CN claimed
CN-219231473-U Crystallization equipment of disodium uridine diphosphate 江苏香地化学有限公司 2023-06-23 — — CN claimed
CN-114836398-B Application of glycosyltransferase mutant in directional synthesis of non-natural ginsenoside 南京工业大学 2023-06-23 — — CN claimed
CN-116144623-A Glycosyltransferase mutant and application thereof in preparing rare ginsenoside by enzymatic method 南京工业大学 2023-05-23 — — CN claimed
CN-111662350-B Preparation method of green intelligent high-purity diquafosol tetrasodium 南京宸翔医药研究有限责任公司 2022-06-07 — — CN claimed
CN-109021049-B Synthesis method of uridine 5' -diphosphate-benzimidazole disodium 扬子江药业集团北京海燕药业有限公司 2020-12-08 — — CN claimed
CN-211585283-U Disodium uridine diphosphate crystallization kettle 美亚药业海安有限公司 2020-09-29 — — CN claimed
CN-111662350-A Preparation method of green intelligent high-purity diquafosol tetrasodium 南京宸翔医药研究有限责任公司 2020-09-15 — — CN claimed
CN-108739195-B Efficient improved peanut seed breeding method 吉林省农业科学院 2020-08-07 — — CN claimed
CN-108739195-A A kind of efficient peanut stock breeding method 吉林省农业科学院 2018-11-06 — — CN claimed
US-12533371-B2 Multilayer pharmaceutical or nutraceutical solid dosage forms comprising pyrimidine and/or purine derivatives and b vitamins, preparation and uses thereof FERRER INTERNACIONAL, S.A. (ES) 2026-01-27 — — US disclosed
EP-4667479-A1 POLYPHOSPHORYLATED NUCLEOSIDE, PHOSPHATE-ACTIVATED NUCLEOTIDE USED FOR SYNTHESIS OF POLYPHOSPHORYLATED NUCLEOSIDE AND METHOD FOR SYNTHESIS OF SAME, AND METHOD FOR SYNTHESIS OF POLYPHOSPHORYLATED NUCLEOSIDE USING PHOSPHATE-ACTIVATED NUCLEOTIDE Natias Inc. (JP) 2025-12-24 — — EP disclosed
EP-1012154-A2 SALTS OF DI(URIDINE 5'-TETRAPHOSPHATE), METHOD FOR PREPARATION AND USES THEREOF Inspire Pharmaceuticals, Inc. (US) 2000-06-28 — — EP disclosed
WO-1999005155-A2 SALTS OF DI(URIDINE 5'-TETRAPHOSPHATE), METHOD FOR PREPARATION AND USES THEREOF INSPIRE PHARMACEUTICALS, INC. (US) 1999-02-04 — — WO disclosed
US-4058601-A URIDINE DIPHOSPHATE CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) 1977-11-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12533371-B2 Multilayer pharmaceutical or nutraceutical solid dosage forms comprising pyrimidine and/or purine derivatives and b vitamins, preparation and uses thereof P2RY10, TYMP, P2RY12 P2RY2 42/4885P2RY6 17/4885P2RY4 37/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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