Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MPL | P40238 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6630838 | 0.88 | TAS2R14 (0.46) | NOTUMTAS2R14HSD11B1KIF11PARP1 | |
| SCHEMBL11955140 | 0.79 | CA2 (0.46) | NOTUMTAS2R14HSD11B1KIF11PARP1 | |
| SCHEMBL2276181 | 0.77 | TAS2R14 (0.40) | NOTUMTAS2R14HSD11B1KIF11PARP1 | |
| SCHEMBL3821590 | 0.76 | TRPA1 (0.48) | NOTUMTAS2R14HSD11B1P2RX7CTSS | |
| SCHEMBL30867018 | 0.76 | TRPA1 (0.48) | NOTUMTAS2R14HSD11B1P2RX7CTSS | |
| SCHEMBL18966067 | 0.76 | TAS2R14 (0.39) | NOTUMTAS2R14HSD11B1KIF11PARP1 | |
| SCHEMBL20342924 | 0.76 | NOTUM (0.41) | NOTUMTAS2R14HSD11B1P2RX7CTSS | |
| SCHEMBL173020 | 0.74 | HSD11B1 (0.45) | NOTUMTAS2R14HSD11B1KIF11P2RX7 | |
| SCHEMBL942703 | 0.74 | P2RX7 (0.41) | NOTUMTAS2R14HSD11B1KIF11PARP1 | |
| SCHEMBL18965951 | 0.74 | TAS2R14 (0.45) | NOTUMTAS2R14HSD11B1KIF11P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2802594-B1 | METAL COMPLEXES WITH DIBENZO[F,H]QUINOXALINES | UDC IRELAND LTD (IE) | 2017-04-19 | — | — | EP | disclosed |