Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | WEE1 | P30291 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17928546 | 0.74 | BCHE (0.46) | BCHEACHEALOX5PTGS1PTGS2 | |
| SCHEMBL11808516 | 0.70 | BCHE (0.67) | BCHEACHEALOX5PTGS1PTGS2 | |
| SCHEMBL3874806 | 0.68 | BCHE (0.56) | BCHEACHEALOX5PTGS1PTGS2 | |
| SCHEMBL5857121 | 0.66 | AS3MT (0.56) | BCHEACHEALOX5PTGS1PTGS2 | |
| SCHEMBL9095202 | 0.65 | ALOX5 (0.53) | ALOX5MEN1KMT2ASPRALOX15 | |
| SCHEMBL2403408 | 0.64 | KDM4E (0.49) | ALOX5MEN1KMT2AALOX15EGFR | |
| SCHEMBL20384979 | 0.63 | ACHE (0.57) | BCHEACHEALOX5PTGS1PTGS2 | |
| SCHEMBL27985040 | 0.63 | GPR3 (0.64) | BCHEACHEALOX5PTGS1PTGS2 | |
| SCHEMBL12926001 | 0.63 | MAPT (0.53) | BCHEACHEALOX5PTGS1PTGS2 | |
| SCHEMBL1093460 | 0.62 | ACLY (0.47) | F2RL3KDM4EALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066661-A1 | Non-Selective Protease Activated Receptor 4 Ala120Thr Isoform Antagonist | THOMAS JEFFERSON UNIVERSITY (US) | 2017-04-20 | — | — | WO | disclosed |