Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1239685 | 0.98 | DNM1 (0.44) | DNM1SMN1; SMN2MEN1KMT2AMAPK1 | |
| Fluoride Ion SCHEMBL27700191 | 0.95 | DNM1 (0.42) | DNM1SMN1; SMN2MEN1KMT2AMAPK1 | |
| Iodide SCHEMBL5087257 | 0.95 | APOBEC3A (0.44) | DNM1SMN1; SMN2MEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL126374 | 0.95 | SMN1; SMN2 (0.46) | DNM1SMN1; SMN2MEN1KMT2AMAPK1 | |
| Bromide SCHEMBL5091360 | 0.95 | DNM1 (0.46) | DNM1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL14560951 | 0.93 | DNM1 (0.50) | DNM1SMN1; SMN2MEN1KMT2AMAPK1 | |
| Water SCHEMBL29140164 | 0.91 | DNM1 (0.53) | DNM1SMN1; SMN2MEN1KMT2AMAPK1 | |
| Water SCHEMBL28989282 | 0.91 | DNM1 (0.53) | DNM1SMN1; SMN2MEN1KMT2AMAPK1 | |
| Water SCHEMBL11776923 | 0.91 | DNM1 (0.40) | DNM1SMN1; SMN2MEN1KMT2AMAPK1 | |
| Water SCHEMBL11425658 | 0.89 | DNM1 (0.47) | DNM1SMN1; SMN2MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 504 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116589921-B | Silicon-rich anti-reflection coating resin material and preparation method thereof | 宁波杭州湾新材料研究院 | 2024-12-03 | — | — | CN | claimed |
| CN-116589921-A | Silicon-rich anti-reflection coating resin material and preparation method thereof | 宁波杭州湾新材料研究院 | 2023-08-15 | — | — | CN | claimed |
| CN-110471262-A | A kind of colored filter developer composition | HUAPU MICROELECTRONIC TECH NINGBO CO LTD | 2019-11-19 | — | — | CN | claimed |
| EP-2844310-B1 | SHAPE-MEMORY CROSS-LINKED POLYSACCHARIDES | MEDICAL AND BIOTECHNOLOGICAL SERVICES SRL IN ABBREVIATED FORM M B S SRL (IT) | 2017-09-06 | — | — | EP | claimed |
| EP-2844310-A1 | SHAPE-MEMORY CROSS-LINKED POLYSACCHARIDES | Medical and Biotechnological Services Srl M.B.S. Srl (IT) | 2015-03-11 | — | — | EP | claimed |
| CN-103901021-A | Kit for rapid identification of waste edible oil | LANZHOU CHEM PHYS INST | 2014-07-02 | — | — | CN | claimed |
| WO-2013164782-A1 | SHAPE-MEMORY CROSS-LINKED POLYSACCHARIDES | MEDICAL AND BIOTECHNOLOGICAL SERVICES SRL IN ABBREVIATED FORM M.B.S. SRL (IT) | 2013-11-07 | — | — | WO | claimed |
| CN-122037155-A | Hollow container and method for producing polycarbonate resin | 三菱化学株式会社 | 2026-05-15 | — | — | CN | disclosed |
| EP-2371877-B1 | POLYCARBONATE RESIN, POLYCARBONATE RESIN COMPOSITION, OPTICAL FILM, AND POLYCARBONATE RESIN MOLDED ARTICLE | MITSUBISHI CHEM CORP (JP) | 2026-04-29 | — | — | EP | disclosed |
| US-20260098129-A1 | THERMOPLASTIC RESIN AND MOLDED BODY CONTAINING THERMOPLASTIC RESIN | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2026-04-09 | — | — | US | disclosed |
| US-20260071030-A1 | THERMOPLASTIC RESIN, MOLDED BODY CONTAINING THERMOPLASTIC RESIN, AND OPTICAL LENS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2026-03-12 | — | — | US | disclosed |
| US-20260062520-A1 | THERMOPLASTIC RESIN AND MOLDED OBJECT INCLUDING THERMOPLASTIC RESIN | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2026-03-05 | — | — | US | disclosed |
| EP-4129965-B1 | THERMOPLASTIC RESIN HAVING CARBONATE BOND | MITSUBISHI CHEM CORP (JP) | 2025-12-17 | — | — | EP | disclosed |
| US-4360421-A | Method for treating mercaptans contained in a sour petroleum distillate | UOP INC. (US) | 1982-11-23 | — | — | US | disclosed |
| US-4320029-A | Catalytic composite, method of manufacture, and process for use | UOP INC. (US) | 1982-03-16 | — | — | US | disclosed |
| US-4308169-A | TREATMENT WITH AQUEOUS SOLUTION OF QUATERNARY AMMONIUM COMPOUND AND LINEAR IONIC COMPOUND | UOP INC. (US) | 1981-12-29 | — | — | US | disclosed |
| US-4299729-A | TREATING WITH AN AMMONIACAL SOLUTION OF A METAL CHELATE AND AN AQUEOUS SOLUTION OF A QUATERNARY AMMONIUM COMPOUND | UOP INC. (US) | 1981-11-10 | — | — | US | disclosed |
| US-4298463-A | Method of treating a sour petroleum distillate | UOP INC. (US) | 1981-11-03 | — | — | US | disclosed |
| US-4213877-A | Method of reactivating a catalytic composite of an adsorptive carrier material and a mercaptan oxidation catalyst | UOP INC. (US) | 1980-07-22 | — | — | US | disclosed |
| US-4203827-A | Process for treating sour petroleum distillates | UOP INC. (US) | 1980-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260062520-A1 | THERMOPLASTIC RESIN AND MOLDED OBJECT INCLUDING THERMOPLASTIC RESIN | RER1, PUF60, SEM1 | DNM1 2852/4885SMN1; SMN2 1888/4885MEN1 1038/4885 |
| US-20260071030-A1 | THERMOPLASTIC RESIN, MOLDED BODY CONTAINING THERMOPLASTIC RESIN, AND OPTICAL LENS | DERL1, WDR1, RIF1 | DNM1 2540/4885SMN1; SMN2 3023/4885MEN1 518/4885 |
| US-20260098129-A1 | THERMOPLASTIC RESIN AND MOLDED BODY CONTAINING THERMOPLASTIC RESIN | RER1, EIF2AK1, RIOK1 | DNM1 3740/4885SMN1; SMN2 2123/4885MEN1 1020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.