Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18784242 | 0.86 | CSNK2A1 (0.40) | KDM4ESMN1; SMN2SPHK1HTR6CSNK2A1 | |
| SCHEMBL18784252 | 0.86 | KDM4E (0.41) | ALDH1A1KDM4ESPHK1HTR6HRH1 | |
| SCHEMBL18784223 | 0.85 | CSNK2A1 (0.39) | SMN1; SMN2SPHK1HTR6CSNK2A1 | |
| SCHEMBL18784214 | 0.82 | CSNK2A1 (0.36) | KDM4ESPHK1CSNK2A1 | |
| SCHEMBL18784248 | 0.78 | HTR7 (0.38) | HTR7ALDH1A1KDM4ESMN1; SMN2ADRB2 | |
| SCHEMBL18784213 | 0.76 | SLC6A4 (0.36) | HTR6CSNK2A1 | |
| SCHEMBL18784228 | 0.76 | CSNK2A1 (0.41) | HTR7DRD2HTR6CSNK2A1 | |
| Hydrochloric Acid SCHEMBL1647980 | 0.76 | METAP2 (0.42) | HTR7ALDH1A1KDM4ESMN1; SMN2GBA1 | |
| SCHEMBL18784233 | 0.74 | BRD4 (0.41) | ALDH1A1KDM4ESMN1; SMN2CSNK2A1 | |
| SCHEMBL1648648 | 0.73 | ALDH1A1 (0.35) | ALDH1A1KDM4ESMN1; SMN2GBA1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486004-B1 | SULPHONE COMPOUNDS FOR USE IN THE TREATMENT OF OBESITY | ZAFGEN INC (US) | 2017-05-03 | — | — | EP | claimed |