Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18797100 | 0.84 | CYP3A4 (0.34) | CCNT1CCNE1CDK2CDK9MAPT | |
| SCHEMBL18797608 | 0.81 | CDK8 (0.40) | MAPTCDK8ACVR1 | |
| SCHEMBL15935620 | 0.69 | ESR2 (0.42) | MAPTCDK8ACVR1 | |
| SCHEMBL24252130 | 0.69 | L3MBTL1 (0.35) | MAPTCDK8ACVR1 | |
| SCHEMBL11965000 | 0.68 | CDK8 (0.44) | MAPTCDK8ACVR1 | |
| SCHEMBL18797101 | 0.68 | MAOA (0.41) | MAPTCDK8ACVR1NR3C2 | |
| SCHEMBL17224789 | 0.67 | DHFR (0.43) | MAPTCDK8ACVR1 | |
| SCHEMBL30576349 | 0.67 | DHFR (0.43) | MAPTCDK8ACVR1 | |
| SCHEMBL29457662 | 0.67 | KMT2A (0.36) | MAPTCDK8ACVR1 | |
| SCHEMBL22031802 | 0.67 | KMT2A (0.36) | MAPTCDK8ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3368523-B1 | NOVEL PYRIDAZINONE HERBICIDES | FMC CORP (US) | 2021-07-14 | — | — | EP | disclosed |
| CN-108495849-B | Pyridazinone herbicides | FMC公司 | 2020-11-10 | — | — | CN | disclosed |
| US-10750743-B2 | Pyridazinone herbicides | FMC CORPORATION (US) | 2020-08-25 | — | — | US | disclosed |
| US-20180332851-A1 | NOVEL PYRIDAZINONE HERBICIDES | FMC CORPORATION | 2018-11-22 | — | — | US | disclosed |
| EP-3368523-A1 | NOVEL PYRDAZINONE HERBICIDES | E. I. du Pont de Nemours and Company (US) | 2018-09-05 | — | — | EP | disclosed |
| WO-2017074992-A1 | NOVEL PYRDAZINONE HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2017-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10750743-B2 | Pyridazinone herbicides | PRDX4, PRDX6, PDXK | CCNT1 440/4885CCNE1 398/4885CDK2 263/4885 |
| US-20180332851-A1 | NOVEL PYRIDAZINONE HERBICIDES | PRDX4, PRDX6, PDXK | CCNT1 597/4885CCNE1 453/4885CDK2 290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.