Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 4/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18797102 | 0.83 | COMT (0.36) | LMNAMAPTMAPK1CYP3A4HPGD | |
| SCHEMBL20522633 | 0.80 | ALDH1A1 (0.41) | LMNAMAPTHPGDKDM4ENPBWR1 | |
| SCHEMBL21835495 | 0.80 | NPBWR1 (0.41) | LMNAMAPTHPGDKMT2ANPBWR1 | |
| SCHEMBL29382816 | 0.80 | NPBWR1 (0.41) | LMNAMAPTHPGDKMT2ANPBWR1 | |
| SCHEMBL20522632 | 0.77 | SMN1; SMN2 (0.37) | LMNAMAPK1HPGDKDM4EHTT | |
| SCHEMBL22977710 | 0.71 | CNR2 (0.42) | MAPTMAPK1HPGDKMT2APOLB | |
| SCHEMBL29386231 | 0.69 | NPBWR1 (0.35) | LMNAMAPTMAPK1HPGDKMT2A | |
| SCHEMBL21835493 | 0.69 | NPBWR1 (0.35) | LMNAMAPTMAPK1HPGDKMT2A | |
| SCHEMBL29058622 | 0.68 | ALDH1A1 (0.36) | LMNAMAPTMAPK1HPGDKMT2A | |
| SCHEMBL12223316 | 0.67 | PLAU (0.56) | LMNAMAPTMAPK1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3368523-B1 | NOVEL PYRIDAZINONE HERBICIDES | FMC CORP (US) | 2021-07-14 | — | — | EP | disclosed |
| CN-108495849-B | Pyridazinone herbicides | FMC公司 | 2020-11-10 | — | — | CN | disclosed |
| US-10750743-B2 | Pyridazinone herbicides | FMC CORPORATION (US) | 2020-08-25 | — | — | US | disclosed |
| US-20180332851-A1 | NOVEL PYRIDAZINONE HERBICIDES | FMC CORPORATION | 2018-11-22 | — | — | US | disclosed |
| EP-3368523-A1 | NOVEL PYRDAZINONE HERBICIDES | E. I. du Pont de Nemours and Company (US) | 2018-09-05 | — | — | EP | disclosed |
| WO-2017074992-A1 | NOVEL PYRDAZINONE HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2017-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10750743-B2 | Pyridazinone herbicides | PRDX4, PRDX6, PDXK | LMNA 3603/4885MAPT 4541/4885MAPK1 1116/4885 |
| US-20180332851-A1 | NOVEL PYRIDAZINONE HERBICIDES | PRDX4, PRDX6, PDXK | LMNA 4063/4885MAPT 4559/4885MAPK1 1209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.