Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20522632 | 0.86 | SMN1; SMN2 (0.37) | ALDH1A1KDM4EHPGDLMNASMN1; SMN2 | |
| SCHEMBL29382816 | 0.86 | NPBWR1 (0.41) | ALDH1A1HPGDNPBWR1LMNASMN1; SMN2 | |
| SCHEMBL21835495 | 0.86 | NPBWR1 (0.41) | ALDH1A1HPGDNPBWR1LMNASMN1; SMN2 | |
| SCHEMBL29058622 | 0.85 | ALDH1A1 (0.36) | ALDH1A1NPSR1HPGDNPBWR1LMNA | |
| SCHEMBL29058636 | 0.81 | SMN1; SMN2 (0.37) | ALDH1A1NPSR1KDM4EHPGDNPBWR1 | |
| SCHEMBL20522637 | 0.81 | NPEPPS (0.37) | NPSR1HPGDLMNASMN1; SMN2GAA | |
| SCHEMBL18797107 | 0.80 | LMNA (0.36) | ALDH1A1NPSR1KDM4EHPGDNPBWR1 | |
| SCHEMBL21835493 | 0.75 | NPBWR1 (0.35) | ALDH1A1NPSR1HPGDNPBWR1LMNA | |
| SCHEMBL29386231 | 0.75 | NPBWR1 (0.35) | ALDH1A1NPSR1HPGDNPBWR1LMNA | |
| SCHEMBL22977710 | 0.72 | CNR2 (0.42) | ALDH1A1HPGDNPBWR1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11292770-B2 | Pyridazinone herbicides | FMC CORPORATION (US) | 2022-04-05 | — | — | US | disclosed |
| EP-3601263-B1 | NOVEL PYRIDAZINONE HERBICIDES | FMC CORP (US) | 2021-10-13 | — | — | EP | disclosed |
| US-20200109123-A1 | NOVEL PYRIDAZINONE HERBICIDES | FMC CORPORATION | 2020-04-09 | — | — | US | disclosed |
| EP-3601263-A1 | NOVEL PYRIDAZINONE HERBICIDES | FMC Corporation (US) | 2020-02-05 | — | — | EP | disclosed |
| CN-110741000-A | Novel pyridazinone herbicides | FMC公司 | 2020-01-31 | — | — | CN | disclosed |
| WO-2018183432-A1 | NOVEL PYRIDAZINONE HERBICIDES | FMC CORPORATION (US) | 2018-10-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11292770-B2 | Pyridazinone herbicides | PRDX6, PRDX4, PDXK | ALDH1A1 287/4885NPSR1 2414/4885KDM4E 1848/4885 |
| US-20200109123-A1 | NOVEL PYRIDAZINONE HERBICIDES | PRDX6, PRDX4, CHRM2 | ALDH1A1 383/4885NPSR1 2296/4885KDM4E 1703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.