Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 7/20 | 0.51 |
| ▸ | MLNR | O43193 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18801363 | 0.87 | L3MBTL1 (0.47) | MEN1KMT2AALOX5GAAMLNR | |
| SCHEMBL1648072 | 0.85 | MAPT (0.47) | MEN1KMT2AALOX5GAAMLNR | |
| SCHEMBL1647924 | 0.79 | LMNA (0.47) | MEN1KMT2AALOX5GAAMLNR | |
| SCHEMBL18801179 | 0.78 | LMNA (0.45) | MEN1KMT2AALOX5GAAMLNR | |
| SCHEMBL18801320 | 0.78 | LMNA (0.47) | MEN1KMT2AALOX5GAAMLNR | |
| SCHEMBL1649989 | 0.77 | MAPK1 (0.52) | MEN1KMT2AGAAMAPTMAPK1 | |
| SCHEMBL18801332 | 0.76 | L3MBTL1 (0.52) | MEN1KMT2AALOX5MAPTRECQL | |
| SCHEMBL18801099 | 0.74 | ALOX5 (0.48) | MEN1KMT2AALOX5GAAMLNR | |
| SCHEMBL7278764 | 0.73 | ALDH1A1 (0.43) | MEN1KMT2AALOX5GAAMAPT | |
| SCHEMBL1648194 | 0.73 | L3MBTL1 (0.46) | MEN1KMT2AALOX5MAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486004-B1 | SULPHONE COMPOUNDS FOR USE IN THE TREATMENT OF OBESITY | ZAFGEN INC (US) | 2017-05-03 | — | — | EP | disclosed |