SCHEMBL188131

SCHEMBL188131

NC(C(=O)O)C1CCNCC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPN1 P15169 2/20 0.52
CPB2 Q96IY4 2/20 0.52
PMP22 Q01453 2/20 0.44
GABRP O00591 1/20 0.44
GABRD O14764 1/20 0.44
GABRA1 P14867 1/20 0.44
TSHR P16473 1/20 0.44
GABRB1 P18505 1/20 0.44
GABRG2 P18507 1/20 0.44
GABRB3 P28472 1/20 0.44
GABRA5 P31644 1/20 0.44
GABRA3 P34903 1/20 0.44
GABRA2 P47869 1/20 0.44
GABRB2 P47870 1/20 0.44
GABRA4 P48169 1/20 0.44
GABRE P78334 1/20 0.44
GABRA6 Q16445 1/20 0.44
GABRG1 Q8N1C3 1/20 0.44
GABRG3 Q99928 1/20 0.44
GABRQ Q9UN88 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1527375 1.00 CPN1 (0.52) CPN1CPB2PMP22GABRPGABRD
SCHEMBL1764002 1.00 CPN1 (0.52) CPN1CPB2PMP22GABRPGABRD
Hydrochloric Acid SCHEMBL7130720 0.98 CPN1 (0.50) CPN1CPB2PMP22GABRPGABRD
SCHEMBL2262916 0.87 CPN1 (0.44) CPN1CPB2PMP22GABRPGABRD
SCHEMBL1531463 0.83
SCHEMBL412802 0.83
SCHEMBL412803 0.83
SCHEMBL2462366 0.82 DPP4 (0.43) CPN1CPB2PMP22GABRPGABRD
SCHEMBL18739352 0.82 DPP4 (0.43) CPN1CPB2PMP22GABRPGABRD
SCHEMBL29357273 0.82 DPP4 (0.43) CPN1CPB2PMP22GABRPGABRD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 424 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 US claimed
US-12351573-B2 Compounds for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2025-07-08 US claimed
CN-117126248-A Novel heterodimer positron emission tomography developer 核欣(苏州)医药科技有限公司 2023-11-28 CN claimed
US-20230111252-A1 THIOSEMICARBAZATES AND USES THEREOF THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2023-04-13 US claimed
US-20220372022-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2022-11-24 US claimed
US-20220125781-A1 Methods and Compositions for Treating Vasomotor Symptoms UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION 2022-04-28 US claimed
CN-113454098-A Radiolabeled bombesin derivative compounds for in vivo imaging of Gastrin Releasing Peptide Receptor (GRPR) and treatment of GRPR related disorders 省卫生服务机构 2021-09-28 CN claimed
US-20210030745-A9 Methods and Compositions for Treating Vasomotor Symptoms ACER THERAPEUTICS INC. 2021-02-04 US claimed
US-20190255037-A1 Methods and Compositions for Treating Vasomotor Symptoms UNIV WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2019-08-22 US claimed
US-20190177365-A1 SYNTHETIC PEPTIDE AMIDES AND DIMERS THEREOF CARA THERAPEUTICS, INC. (US) 2019-06-13 US claimed
US-20090075907-A1 SYNTHETIC PEPTIDE AMIDES CARA THERAPEUTICS, INC. (US) 2009-03-19 US claimed
WO-2008110695-A1 NOVEL MULTIMERIC MOLECULES, METHOD FOR PREPARING SAME AND USE THEREOF IN THE PREPARATION OF DRUGS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2008-09-18 WO claimed
WO-2008060552-A2 SYNTHETIC PEPTIDE AMIDES AND DIMERS THEREOF CARA THERAPEUTICS, INC. (US) 2008-05-22 WO claimed
WO-2008057608-A2 SYNTHETIC PEPTIDE AMIDES CARA THERAPEUTICS, INC. (US) 2008-05-15 WO claimed
US-7368432-B2 Conotoxin peptides XENOME, LTD. (AU) 2008-05-06 US claimed
US-20080081901-A1 ALPHA-CONOTOXIN PEPTIDES THE UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2008-04-03 US claimed
US-7279549-B2 Apha-conotoxin peptides THE UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2007-10-09 US claimed
EP-1828240-A2 NOVEL MULTIMERIC CD40 LIGANDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR PREPARING DRUGS The Centre National de la Recherche Scientifique (FR) 2007-09-05 EP claimed
WO-2006064133-A2 NOVEL MULTIMERIC CD40 LIGANDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR PREPARING DRUGS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2006-06-22 WO claimed
US-6797808-B1 FOUND NATURALLY IN VENOM OF THE CONE SNAILS; HAVE SPECIFICITY FOR NEURONAL NICOTINIC ACETYLCHOLINE RECEPTORS; FOR TREATING CARDIOVASCULAR, GASTRIC MOTILITY, AND MOOD DISORDERS, URINARY INCONTINENCE, NICOTINE ADDICTION, AND SMALL CELL LUNG CANCER UNIVERSITY OF UTAH RESEARCH FOUNDATION 2004-09-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12351573-B2 Compounds for use in synthesis of peptidomimetics DNPEP, NPEPPS, PAM CPN1 209/4885CPB2 707/4885PMP22 1225/4885
US-20210030745-A9 Methods and Compositions for Treating Vasomotor Symptoms VASP, PDE3A, PDE2A CPN1 3127/4885CPB2 943/4885PMP22 622/4885
US-20190255037-A1 Methods and Compositions for Treating Vasomotor Symptoms VASP, PDE3A, PDE2A CPN1 3127/4885CPB2 943/4885PMP22 622/4885
US-20230111252-A1 THIOSEMICARBAZATES AND USES THEREOF TST, ABAT, AADAC CPN1 229/4885CPB2 395/4885PMP22 2452/4885
US-20090075907-A1 SYNTHETIC PEPTIDE AMIDES VIP, OPRK1, OPRL1 CPN1 2110/4885CPB2 2863/4885PMP22 880/4885
US-20220372022-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS DNPEP, NPEPPS, PAM CPN1 209/4885CPB2 707/4885PMP22 1225/4885
US-20220125781-A1 Methods and Compositions for Treating Vasomotor Symptoms VASP, PDE3A, PDE2A CPN1 3127/4885CPB2 943/4885PMP22 622/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT CPN1 124/4885CPB2 761/4885PMP22 3515/4885
US-20190177365-A1 SYNTHETIC PEPTIDE AMIDES AND DIMERS THEREOF OPRK1, OPRL1, OPRM1 CPN1 574/4885CPB2 514/4885PMP22 1277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.