SCHEMBL18819235

SCHEMBL18819235

c1ccc(-c2nc(-c3ccccc3)nc(-c3c(-c4ccc(-n5c6ccccc6c6c7ccccc7ccc65)cc4)ccc4ccccc34)n2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 4/20 0.36
▸ ATM Q13315 3/20 0.36
▸ L3MBTL1 Q9Y468 2/20 0.36
▸ MAPT P10636 3/20 0.32
▸ ALDH1A1 P00352 2/20 0.32
▸ HPGD P15428 2/20 0.32
▸ KMT2A Q03164 3/20 0.32
▸ SMN1; SMN2 Q16637 2/20 0.32
▸ NPC1 O15118 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ RECQL P46063 1/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ PTGES O14684 1/20 0.31
▸ MEN1 O00255 2/20 0.31
▸ TP53 P04637 1/20 0.31
▸ TSHR P16473 1/20 0.31
▸ NFKB1 P19838 1/20 0.31
▸ MAPK1 P28482 1/20 0.31
▸ NFKB2 Q00653 1/20 0.31
▸ RELA Q04206 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21524309 0.93 KDM4E (0.39) KDM4EATML3MBTL1MAPTALDH1A1
SCHEMBL23319005 0.92 L3MBTL1 (0.44) KDM4EATML3MBTL1MAPTALDH1A1
SCHEMBL18819162 0.91 ATM (0.36) KDM4EATML3MBTL1MAPTALDH1A1
SCHEMBL24154397 0.91 KDM4E (0.37) KDM4EATML3MBTL1MAPTALDH1A1
SCHEMBL13087042 0.90 ATM (0.43) KDM4EATML3MBTL1MAPTALDH1A1
SCHEMBL24152085 0.89 KDM4E (0.36) KDM4EATML3MBTL1MAPTALDH1A1
SCHEMBL21524307 0.89 ATM (0.42) KDM4EATML3MBTL1MAPTKMT2A
SCHEMBL17943428 0.89 ATM (0.42) KDM4EATML3MBTL1MAPTKMT2A
SCHEMBL22352388 0.89 ATM (0.42) KDM4EATML3MBTL1MAPTKMT2A
SCHEMBL17943398 0.89 ATM (0.42) KDM4EATML3MBTL1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11737357-B2 Compound and organic light-emitting device comprising same LG CHEM, LTD. 2023-08-22 — — US disclosed
US-11737357-B2 Compound and organic light-emitting device comprising same LG CHEM, LTD. 2023-08-22 — — US disclosed
US-20230255104-A1 Compound And Organic Light-Emitting Device Comprising Same LG CHEM, LTD. (KR) 2023-08-10 — — US disclosed
US-20230255104-A1 Compound And Organic Light-Emitting Device Comprising Same LG CHEM, LTD. (KR) 2023-08-10 — — US disclosed
EP-3351537-B1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEMICAL LTD (KR) 2023-01-18 — — EP disclosed
US-20230009458-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-01-12 — — US disclosed
US-20220416171-A1 ORGANIC ELECTROLUMINESCENT DEVICE CONFIGURED TO EMIT LIGHT WITH HIGH LUMINOUS EFFICIENCY IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-29 — — US disclosed
US-20220173334-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS EQUIPPED WITH THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2022-06-02 — — US disclosed
US-20220165964-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS PROVIDED WITH THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2022-05-26 — — US disclosed
US-20220059775-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS USING THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2022-02-24 — — US disclosed
US-20210296591-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPLIANCE USING THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2021-09-23 — — US disclosed
EP-3351536-B1 ORGANIC LIGHT-EMITTING DEVICE LG CHEMICAL LTD (KR) 2021-07-21 — — EP disclosed
US-10367149-B2 Organic light-emitting device LG CHEM, LTD. (KR) 2019-07-30 — — US disclosed
US-20190055222-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2019-02-21 — — US disclosed
EP-3351537-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG Chem, Ltd. (KR) 2018-07-25 — — EP disclosed
EP-3351536-A1 ORGANIC LIGHT-EMITTING DEVICE LG Chem, Ltd. (KR) 2018-07-25 — — EP disclosed
WO-2017074052-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2017-05-04 — — WO disclosed
WO-2017074053-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2017-05-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11737357-B2 Compound and organic light-emitting device comprising same CRY1, CYP1B1, CYP1A1 KDM4E 3410/4885ATM 3363/4885L3MBTL1 2353/4885
US-20230255104-A1 Compound And Organic Light-Emitting Device Comprising Same ARL1, AR, ALG3 KDM4E 3327/4885ATM 1043/4885L3MBTL1 696/4885
US-10367149-B2 Organic light-emitting device CRY1, PPOX, CRY2 KDM4E 3639/4885ATM 1926/4885L3MBTL1 43/4885
US-20220165964-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS PROVIDED WITH THE SAME LEF1, OR10J3, RER1 KDM4E 2867/4885ATM 3029/4885L3MBTL1 691/4885
US-20190055222-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CRY1, CYP1B1, CYP1A1 KDM4E 3410/4885ATM 3363/4885L3MBTL1 2353/4885
US-20210296591-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPLIANCE USING THE SAME OLA1, AOC1, ODC1 KDM4E 1043/4885ATM 2227/4885L3MBTL1 835/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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