SCHEMBL18819388

SCHEMBL18819388

c1ccc(-c2nc(-c3ccccc3)nc(-c3c(-c4ccc(-c5ccc6c7ccccc7n(-c7ccccc7)c6c5)cc4)ccc4ccccc34)n2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.41
▸ KDM4E B2RXH2 1/20 0.41
▸ ATM Q13315 1/20 0.41
▸ AVPR1A P37288 1/20 0.35
▸ KMT2A Q03164 3/20 0.34
▸ PTGER4 P35408 1/20 0.33
▸ GPR84 Q9NQS5 1/20 0.33
▸ F2 P00734 1/20 0.32
▸ F10 P00742 1/20 0.32
▸ PRSS1 P07477 1/20 0.32
▸ MAPT P10636 3/20 0.32
▸ MEN1 O00255 2/20 0.32
▸ HSP90AA1 P07900 1/20 0.32
▸ ESR1 P03372 1/20 0.32
▸ ESR2 Q92731 1/20 0.32
▸ HDAC4 P56524 1/20 0.32
▸ IL1R1 P14778 1/20 0.32
▸ NPC1 O15118 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23319005 0.91 L3MBTL1 (0.44) L3MBTL1KDM4EATMKMT2AMAPT
SCHEMBL20596300 0.89 L3MBTL1 (0.49) L3MBTL1KDM4EATMAVPR1AKMT2A
SCHEMBL25679991 0.89 KDM4E (0.39) L3MBTL1KDM4EATMKMT2APTGER4
SCHEMBL20404895 0.89 KDM4E (0.38) L3MBTL1KDM4EATMKMT2APTGER4
SCHEMBL25679966 0.87 ATM (0.41) L3MBTL1KDM4EATMKMT2APTGER4
SCHEMBL26432183 0.87 KDM4E (0.38) L3MBTL1KDM4EATMAVPR1AKMT2A
SCHEMBL22639426 0.87 ATM (0.42) L3MBTL1KDM4EATMAVPR1AKMT2A
SCHEMBL16943252 0.87 L3MBTL1 (0.55) L3MBTL1KDM4EATMAVPR1AKMT2A
SCHEMBL22639431 0.86 KDM4E (0.38) L3MBTL1KDM4EATMKMT2AGPR84
SCHEMBL22639425 0.86 KDM4E (0.38) L3MBTL1KDM4EATMKMT2AGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11737357-B2 Compound and organic light-emitting device comprising same LG CHEM, LTD. 2023-08-22 — — US disclosed
US-11737357-B2 Compound and organic light-emitting device comprising same LG CHEM, LTD. 2023-08-22 — — US disclosed
US-20230255104-A1 Compound And Organic Light-Emitting Device Comprising Same LG CHEM, LTD. (KR) 2023-08-10 — — US disclosed
US-20230255104-A1 Compound And Organic Light-Emitting Device Comprising Same LG CHEM, LTD. (KR) 2023-08-10 — — US disclosed
EP-3351537-B1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEMICAL LTD (KR) 2023-01-18 — — EP disclosed
US-20220416171-A1 ORGANIC ELECTROLUMINESCENT DEVICE CONFIGURED TO EMIT LIGHT WITH HIGH LUMINOUS EFFICIENCY IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-29 — — US disclosed
US-20220173334-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS EQUIPPED WITH THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2022-06-02 — — US disclosed
US-20220165964-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS PROVIDED WITH THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2022-05-26 — — US disclosed
US-20220059775-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS USING THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2022-02-24 — — US disclosed
US-20210296591-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPLIANCE USING THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2021-09-23 — — US disclosed
EP-3351536-B1 ORGANIC LIGHT-EMITTING DEVICE LG CHEMICAL LTD (KR) 2021-07-21 — — EP disclosed
WO-2020209299-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE COMPRISING SAME 出光興産株式会社 2020-10-15 — — WO disclosed
US-10367149-B2 Organic light-emitting device LG CHEM, LTD. (KR) 2019-07-30 — — US disclosed
US-20190055222-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2019-02-21 — — US disclosed
EP-3351536-A1 ORGANIC LIGHT-EMITTING DEVICE LG Chem, Ltd. (KR) 2018-07-25 — — EP disclosed
EP-3351537-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG Chem, Ltd. (KR) 2018-07-25 — — EP disclosed
WO-2017074052-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2017-05-04 — — WO disclosed
WO-2017074053-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2017-05-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11737357-B2 Compound and organic light-emitting device comprising same CRY1, CYP1B1, CYP1A1 L3MBTL1 2353/4885KDM4E 3410/4885ATM 3363/4885
US-20230255104-A1 Compound And Organic Light-Emitting Device Comprising Same ARL1, AR, ALG3 L3MBTL1 696/4885KDM4E 3327/4885ATM 1043/4885
US-10367149-B2 Organic light-emitting device CRY1, PPOX, CRY2 L3MBTL1 43/4885KDM4E 3639/4885ATM 1926/4885
US-20220165964-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS PROVIDED WITH THE SAME LEF1, OR10J3, RER1 L3MBTL1 691/4885KDM4E 2867/4885ATM 3029/4885
US-20190055222-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CRY1, CYP1B1, CYP1A1 L3MBTL1 2353/4885KDM4E 3410/4885ATM 3363/4885
US-20210296591-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPLIANCE USING THE SAME OLA1, AOC1, ODC1 L3MBTL1 835/4885KDM4E 1043/4885ATM 2227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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