SCHEMBL1882636

SCHEMBL1882636

O=C1C=CC(=O)C(c2cccs2)=C1c1cccs1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.46
MAPT P10636 3/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
ALDH1A1 P00352 2/20 0.46
MEN1 O00255 2/20 0.46
HPGD P15428 2/20 0.46
KMT2A Q03164 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
LTA4H P09960 1/20 0.42
LTK P29376 1/20 0.42
CDK5 Q00535 1/20 0.42
MST1R Q04912 1/20 0.42
DYRK1A Q13627 1/20 0.42
CLK4 Q9HAZ1 1/20 0.42
TYMP P19971 1/20 0.39
DPP4 P27487 1/20 0.38
PTGS2 P35354 1/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2C9 P11712 2/20 0.38
GSK3B P49841 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10745113 0.76 PGR (0.43) KDM4EMAPTL3MBTL1ALDH1A1MEN1
SCHEMBL16369828 0.74 GSK3B (0.56) KDM4EMAPTL3MBTL1ALDH1A1MEN1
SCHEMBL27591872 0.74 MAOB (0.48) KDM4EMAPTL3MBTL1ALDH1A1MEN1
SCHEMBL17627823 0.73 LTA4H (0.46) KDM4EMAPTL3MBTL1ALDH1A1MEN1
SCHEMBL3545 0.73 L3MBTL1 (0.57) KDM4EMAPTL3MBTL1ALDH1A1MEN1
SCHEMBL16291133 0.73 L3MBTL1 (0.57) KDM4EMAPTL3MBTL1ALDH1A1MEN1
SCHEMBL2397573 0.71 GSK3B (0.47) KDM4EMAPTL3MBTL1ALDH1A1MEN1
SCHEMBL338810 0.71 LTA4H (0.70) KDM4EMAPTL3MBTL1ALDH1A1MEN1
SCHEMBL1464252 0.71
Fluoride SCHEMBL491501 0.70 L3MBTL1 (0.55) KDM4EMAPTL3MBTL1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184965-A Polyimide-based polymer, and preparation method and application thereof 华南师范大学 2024-06-14 CN disclosed
US-7935836-B2 Compounds comprising a linear series of five fused carbon rings, and preparation thereof FALLIS ALEXANDER GRAHAM 2011-05-03 US disclosed
US-20100004467-A1 COMPOUNDS COMPRISING A LINEAR SERIES OF FIVE FUSED CARBON RINGS, AND PREPARATION THEREOF FALLIS ALEXANDER GRAHAM 2010-01-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100004467-A1 COMPOUNDS COMPRISING A LINEAR SERIES OF FIVE FUSED CARBON RINGS, AND PREPARATION THEREOF JUP, CDH1, EML4 KDM4E 1071/4885MAPT 1466/4885L3MBTL1 3881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.