Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20239110 | 0.86 | CYP3A4 (0.43) | TDP1CYP3A4TSHRTTRMEN1 | |
| SCHEMBL3292927 | 0.77 | ALOX5 (0.64) | MEN1KMT2AALOX15ALOX12ALDH1A1 | |
| SCHEMBL581997 | 0.73 | CRHBP (0.70) | TDP1CYP3A4TSHRTTRMEN1 | |
| SCHEMBL18224 | 0.73 | CYP3A4 (1.00) | TDP1CYP3A4TSHRTTRMEN1 | |
| SCHEMBL8782146 | 0.73 | APEX1 (0.53) | TDP1CA1CA2CA4CA6 | |
| SCHEMBL69980 | 0.73 | CYP3A4 (0.65) | TDP1CYP3A4TSHRTTRMEN1 | |
| Methane SCHEMBL9716111 | 0.71 | CYP3A4 (0.61) | TDP1CYP3A4TSHRTTRMEN1 | |
| SCHEMBL4340169 | 0.71 | CYP3A4 (0.93) | TDP1CYP3A4TSHRTTRMEN1 | |
| SCHEMBL10546483 | 0.71 | CYP3A4 (0.93) | TDP1CYP3A4TSHRTTRMEN1 | |
| SCHEMBL11020186 | 0.71 | CYP3A4 (0.93) | TDP1CYP3A4TSHRTTRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305798-A2 | OPTICAL STORAGE USING MATERIALS COMPRISING CHROMOPHORE OLIGOMERS WHICH CAN UNDERGO CYCLOADDITION | Riso National Laboratory (DK) | 2003-05-02 | — | — | EP | claimed |
| EP-0828709-B1 | NOVEL PHYSICALLY FUNCTIONAL MATERIALS | OPTILINK AB (SE) | 2002-09-18 | — | — | EP | claimed |
| US-6376655-B1 | APPLYING EXTERNAL STIMULATION; OPTICAL ANISOTROPY | RISO NATIONAL LABORATORY (DK) | 2002-04-23 | — | — | US | claimed |
| US-20020025401-A1 | Optical storage using materials comprising chromophore oligomers which can undergo cycloaddition | OPTILINK AB (SE) | 2002-02-28 | — | — | US | claimed |
| WO-2001097217-A2 | OPTICAL STORAGE USING MATERIALS COMPRISING CHROMOPHORE OLIGOMERS WHICH CAN UNDERGO CYCLOADDITION | OPTILINK AB (SE) | 2001-12-20 | — | — | WO | claimed |
| US-5770625-A | GLUTAMATE RECEPTOR BINDING INHIBITORS; INSECTICIDES; NERVOUS SYSTEM DISORDERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1998-06-23 | — | — | US | claimed |
| EP-0828709-A1 | NOVEL PHYSICALLY FUNCTIONAL MATERIALS | FORSKNINGSCENTER RISO (DK) | 1998-03-18 | — | — | EP | claimed |
| WO-1996038410-A1 | NOVEL PHYSICALLY FUNCTIONAL MATERIALS | Forskningscenter Risø (DK) | 1996-12-05 | — | — | WO | claimed |
| US-3934027-A | 18β-Glycyrrhetinic acid amides useful as antiulcer agents | PFIZER INC. (US) | 1976-01-20 | — | — | US | claimed |
| EP-2402037-B1 | CONTROLLED RELEASE OF PHENOLIC OPIOIDS | SIGNATURE THERAPEUTICS INC (US) | 2019-10-23 | — | — | EP | disclosed |
| US-9223216-B2 | Lithographic printing plate precursor and method of preparing the same | FUJIFILM CORPORATION (JP) | 2015-12-29 | — | — | US | disclosed |
| EP-1015469-B2 | BI- AND TRI-CYCLIC NUCLEOSIDE, NUCLEOTIDE AND OLIGONUCLEOIDE ANALOGUES | EXIQON AS (DK) | 2015-11-18 | — | — | EP | disclosed |
| US-20150148284-A1 | Controlled Release of Phenolic Opioids | PHARMACOFORE, INC. | 2015-05-28 | — | — | US | disclosed |
| US-8921418-B2 | Controlled release of phenolic opioids | SIGNATURE THERAPEUTICS, INC. (US) | 2014-12-30 | — | — | US | disclosed |
| EP-1015469-A2 | BI- AND TRI-CYCLIC NUCLEOSIDE, NUCLEOTIDE AND OLIGONUCLEOIDE ANALOGUES | Exiqon A/S (DK) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999014226-A2 | BI- AND TRI-CYCLIC NUCLEOSIDE, NUCLEOTIDE AND OLIGONUCLEOTIDE ANALOGUES | EXIQON A/S (DK) | 1999-03-25 | — | — | WO | disclosed |
| US-5770625-A | GLUTAMATE RECEPTOR BINDING INHIBITORS; INSECTICIDES; NERVOUS SYSTEM DISORDERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1998-06-23 | — | — | US | disclosed |
| EP-0828709-A1 | NOVEL PHYSICALLY FUNCTIONAL MATERIALS | FORSKNINGSCENTER RISO (DK) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996038410-A1 | NOVEL PHYSICALLY FUNCTIONAL MATERIALS | Forskningscenter Risø (DK) | 1996-12-05 | — | — | WO | disclosed |
| US-3934027-A | 18β-Glycyrrhetinic acid amides useful as antiulcer agents | PFIZER INC. (US) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150148284-A1 | Controlled Release of Phenolic Opioids | OPRK1, OPRM1, OPRD1 | TDP1 1825/4885CYP3A4 17/4885TSHR 1421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.