Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.31 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19375602 | 0.72 | ADORA3 (0.43) | KCNH2TRPC4TRPC5 | |
| SCHEMBL18833575 | 0.68 | — | — | |
| SCHEMBL18834023 | 0.68 | TRPC5 (0.54) | KCNH2TRPC4TRPC5 | |
| SCHEMBL18835375 | 0.66 | TRPC5 (0.54) | KCNH2TRPC4TRPC5 | |
| SCHEMBL18834235 | 0.66 | TRPC5 (0.53) | KCNH2TRPC4TRPC5 | |
| SCHEMBL16364003 | 0.65 | TRPC4 (0.41) | KCNH2TRPC4TRPC5 | |
| SCHEMBL19375435 | 0.64 | P2RX3 (0.30) | — | |
| SCHEMBL18834605 | 0.64 | TRPC5 (0.36) | TRPC4TRPC5 | |
| SCHEMBL18834534 | 0.64 | P2RX3 (0.42) | KCNH2TRPC4TRPC5 | |
| SCHEMBL18834247 | 0.63 | P2RX3 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-05-10 | — | — | EP | disclosed |