SCHEMBL18855010

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11922535	0.85	ALDH1A1 (0.41)	TSHRALDH1A1MAPK1TDP1ZDHHC20
	SCHEMBL21182619	0.82	ALDH1A1 (0.46)	TSHRALDH1A1MAPK1TDP1THRB
	SCHEMBL11920349	0.81	ALDH1A1 (0.39)	TSHRALDH1A1MAPK1TDP1ZDHHC20
	SCHEMBL13862879	0.81	ALDH1A1 (0.39)	TSHRALDH1A1MAPK1TDP1ZDHHC20
	Acrylic Acid SCHEMBL11156213	0.78	TSHR (0.41)	TSHRALDH1A1MAPK1TDP1THRB
	SCHEMBL12358358	0.78	TSHR (0.41)	TSHRALDH1A1THRB
	SCHEMBL17522073	0.78	TSHR (0.38)	TSHRALDH1A1MAPK1TDP1THRB
	SCHEMBL17522064	0.78	ALDH1A1 (0.43)	TSHRALDH1A1MAPK1TDP1THRB
	SCHEMBL4789482	0.77	TSHR (0.54)	TSHRALDH1A1MAPK1TDP1ZDHHC20
	SCHEMBL15337	0.77	TSHR (0.50)	TSHRALDH1A1TDP1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.