Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL33 | O95760 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18862291 | 0.83 | IL33 (1.00) | IL33KMT2AMEN1OPRK1OPRM1 | |
| SCHEMBL18862021 | 0.67 | OPRK1 (0.52) | IL33KMT2AMEN1OPRK1OPRM1 | |
| SCHEMBL23507317 | 0.66 | DRD2 (0.57) | IL33KMT2AMEN1OPRK1OPRM1 | |
| SCHEMBL9539833 | 0.66 | SIGMAR1 (0.58) | KMT2AOPRK1OPRM1KDM4EALDH1A1 | |
| SCHEMBL22639701 | 0.64 | OPRK1 (0.49) | IL33KMT2AMEN1OPRK1OPRM1 | |
| SCHEMBL18306590 | 0.64 | OPRK1 (0.49) | IL33KMT2AMEN1OPRK1OPRM1 | |
| SCHEMBL11509465 | 0.64 | OPRK1 (0.58) | IL33KMT2AMEN1OPRK1OPRM1 | |
| SCHEMBL28519807 | 0.64 | OPRK1 (0.52) | IL33KMT2AMEN1OPRK1OPRM1 | |
| SCHEMBL8542014 | 0.63 | SMN1; SMN2 (0.50) | OPRK1OPRM1DRD2KDM4EALDH1A1 | |
| SCHEMBL11512485 | 0.62 | OPRK1 (0.57) | IL33KMT2AMEN1OPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017083242-A1 | INHIBITORS OF SUPPRESSION OF TUMORIGENCITY 2 (ST2) AND METHODS USING THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2017-05-18 | — | — | WO | disclosed |