SCHEMBL18864262

SCHEMBL18864262

CCS(=O)(=O)c1ccc(-n2cncn2)nc1-c1nc2cc(C(F)(F)F)cnc2n1C

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 2/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ DDR1 Q08345 12/20 0.34
▸ MAPT P10636 1/20 0.32
▸ HCRTR1 O43613 1/20 0.30
▸ EGLN1 Q9GZT9 1/20 0.30
▸ LRRK2 Q5S007 1/20 0.30
▸ KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29766637 1.00 POLB (0.40) POLBSMN1; SMN2DDR1MAPTHCRTR1
SCHEMBL18498626 0.89 POLB (0.41) POLBSMN1; SMN2DDR1EGLN1
SCHEMBL18854927 0.88 KDM4E (0.32) POLBMAPTKDM4E
SCHEMBL18866373 0.88 POLB (0.40) POLBDDR1
SCHEMBL18866479 0.87 POLB (0.39) POLBDDR1
SCHEMBL17383123 0.86 DDR1 (0.36) SMN1; SMN2DDR1KDM4E
SCHEMBL18866471 0.86 POLB (0.39) POLBDDR1
SCHEMBL18866478 0.86 POLB (0.39) POLBDDR1
SCHEMBL18864234 0.86 POLB (0.39) POLBDDR1
SCHEMBL18923941 0.85 POLB (0.38) POLBDDR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250143304-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2025-05-08 — — US claimed
US-20240389596-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2024-11-28 — — US claimed
US-12144349-B2 Pesticidal mixtures comprising a mesoionic compound BASF SE (DE) 2024-11-19 — — US claimed
US-20240315245-A1 INSECT AND ACARINA PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2024-09-26 — — US claimed
US-20240268386-A1 SEED TREATMENT COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2024-08-15 — — US claimed
US-20240260577-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2024-08-08 — — US claimed
US-20240138409-A1 INSECT AND ACARINA PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2024-05-02 — — US claimed
EP-4337016-A1 SEED TREATMENT COMPOSITIONS Syngenta Crop Protection AG (CH) 2024-03-20 — — EP claimed
EP-4294187-A1 INSECT AND ACARINA PEST CONTROL Syngenta Crop Protection AG (CH) 2023-12-27 — — EP claimed
EP-4294185-A1 INSECT AND ACARINA PEST CONTROL Syngenta Crop Protection AG (CH) 2023-12-27 — — EP claimed
WO-2023203038-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2023-10-26 — — WO claimed
WO-2023152340-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2023-08-17 — — WO claimed
WO-2023046853-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2023-03-30 — — WO claimed
WO-2023280999-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2023-01-12 — — WO claimed
WO-2022268815-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2022-12-29 — — WO claimed
WO-2020058010-A1 PESTICIDAL MIXTURES COMPRISING A MESOIONIC COMPOUND BASF SE (DE) 2020-03-26 — — WO claimed
US-20250143304-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2025-05-08 — — US disclosed
US-20240389596-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2024-11-28 — — US disclosed
US-9668482-B1 Fused heterocyclic compound and pest control application thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-06 — — US disclosed
US-20170135348-A1 FUSED HETEROCYCLIC COMPOUND AND PEST CONTROL APPLICATION THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-05-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240138409-A1 INSECT AND ACARINA PEST CONTROL ACACA, ACAT2, CHIA POLB 3705/4885SMN1; SMN2 2969/4885DDR1 4731/4885
US-20240260577-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL H1-2, H1-0, H1-3 POLB 4393/4885SMN1; SMN2 515/4885DDR1 4834/4885
US-20240389596-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL ACACA, ACAT2, ACAT1 POLB 4410/4885SMN1; SMN2 801/4885DDR1 4716/4885
US-20240315245-A1 INSECT AND ACARINA PEST CONTROL ACACA, ACAT2, CHIA POLB 3671/4885SMN1; SMN2 2893/4885DDR1 4739/4885
US-20240268386-A1 SEED TREATMENT COMPOSITIONS FAU, ARF5, BROX POLB 846/4885SMN1; SMN2 3752/4885DDR1 3780/4885
US-20250143304-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL ACACA, ACAT2, ACAA2 POLB 4472/4885SMN1; SMN2 809/4885DDR1 3921/4885
US-12144349-B2 Pesticidal mixtures comprising a mesoionic compound ACHE, DDT, MTX2 POLB 2186/4885SMN1; SMN2 386/4885DDR1 4770/4885
US-20170135348-A1 FUSED HETEROCYCLIC COMPOUND AND PEST CONTROL APPLICATION THEREOF KEAP1, DDT, CYP4B1 POLB 4756/4885SMN1; SMN2 1458/4885DDR1 4530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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