SCHEMBL18873161

SCHEMBL18873161

C=C1c2ccccc2CSc2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.49
▸ CHRM2 P08172 1/20 0.49
▸ ADRA2A P08913 1/20 0.49
▸ CYP2D6 P10635 1/20 0.49
▸ CHRM1 P11229 1/20 0.49
▸ DRD2 P14416 1/20 0.49
▸ ADRA2B P18089 1/20 0.49
▸ ADRA2C P18825 1/20 0.49
▸ CHRM3 P20309 1/20 0.49
▸ SLC6A2 P23975 1/20 0.49
▸ HTR2A P28223 1/20 0.49
▸ HTR2C P28335 1/20 0.49
▸ SLC6A4 P31645 1/20 0.49
▸ ADRA1A P35348 1/20 0.49
▸ HRH1 P35367 1/20 0.49
▸ DRD3 P35462 1/20 0.49
▸ OPRK1 P41145 1/20 0.49
▸ HTR2B P41595 1/20 0.49
▸ MC3R P41968 1/20 0.49
▸ SLC6A3 Q01959 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL216973 0.83 ACHE (0.56) ALDH1A1CHRM2ADRA2ACYP2D6CHRM1
SCHEMBL15395749 0.79 MEN1 (0.41) ALDH1A1CHRM2ADRA2ACYP2D6CHRM1
SCHEMBL19334727 0.76 ACHE (0.48) ALDH1A1CHRM2ADRA2ACYP2D6CHRM1
SCHEMBL31123671 0.76 ACHE (0.59) ALDH1A1CHRM2ADRA2ACYP2D6CHRM1
SCHEMBL86279 0.76 ACHE (0.59) ALDH1A1CHRM2ADRA2ACYP2D6CHRM1
SCHEMBL31510701 0.76 ACHE (0.59) ALDH1A1CHRM2ADRA2ACYP2D6CHRM1
SCHEMBL16865823 0.74 ACHE (0.56) ALDH1A1CHRM2ADRA2ACYP2D6CHRM1
SCHEMBL10196640 0.74 MEN1 (0.43) ALDH1A1CHRM2ADRA2ACYP2D6CHRM1
SCHEMBL18815129 0.73 MEN1 (0.41) ALDH1A1CHRM2ADRA2ACYP2D6CHRM1
SCHEMBL15761043 0.73 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11697695-B2 Polymerizable composition and optically anisotropic body using same DIC CORPORATION (JP) 2023-07-11 — — US disclosed
US-11697695-B2 Polymerizable composition and optically anisotropic body using same DIC CORPORATION (JP) 2023-07-11 — — US disclosed
US-11186669-B2 Polymerizable composition and optically anisotropic body using same DIC CORPORATION (JP) 2021-11-30 — — US disclosed
US-20210284766-A1 RETARDATION FILM, ELLIPTICALLY POLARIZING PLATE, AND DISPLAY DEVICE INCLUDING THE SAME DIC CORPORATION (JP) 2021-09-16 — — US disclosed
US-11046889-B2 Polymerizable compound and optically anisotropic body DIC CORPORATION (JP) 2021-06-29 — — US disclosed
US-10927263-B2 Polymerizable composition and optically anisotropic body produced using the same DIC CORPORATION (JP) 2021-02-23 — — US disclosed
US-10919870-B2 Polymerizable compound and optically anisotropic body DIC CORPORATION (JP) 2021-02-16 — — US disclosed
US-10723952-B2 Polymerizable compound and optically anisotropic body DIC CORPORATION (JP) 2020-07-28 — — US disclosed
US-10649124-B2 Composition including compound having mesogenic group, polymer and optically anisotropic body obtained by polymerizing polymerizable composition, and phase difference film DIC CORPORATION (JP) 2020-05-12 — — US disclosed
US-10479844-B2 Polymerizable composition and optically anisotropic body using same DIC CORPORATION (JP) 2019-11-19 — — US disclosed
US-20180022716-A1 POLYMERIZABLE COMPOUND AND OPTICAL ISOMER DIC CORPORATION (JP) 2018-01-25 — — US disclosed
US-20180022716-A1 POLYMERIZABLE COMPOUND AND OPTICAL ISOMER DIC CORPORATION (JP) 2018-01-25 — — US disclosed
US-20180016502-A1 POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME DIC CORPORATION (JP) 2018-01-18 — — US disclosed
US-20180016502-A1 POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME DIC CORPORATION (JP) 2018-01-18 — — US disclosed
US-20180002459-A1 POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME DIC CORPORATION (JP) 2018-01-04 — — US disclosed
US-20180002460-A1 POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME DIC CORPORATION (JP) 2018-01-04 — — US disclosed
EP-3246340-A1 POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME DIC Corporation (JP) 2017-11-22 — — EP disclosed
US-20170306233-A1 POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY DIC CORPORATION (JP) 2017-10-26 — — US disclosed
US-20170306233-A1 POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY DIC CORPORATION (JP) 2017-10-26 — — US disclosed
WO-2017079867-A1 POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY DIC CORPORATION (JP) 2017-05-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10927263-B2 Polymerizable composition and optically anisotropic body produced using the same CRYAA, IK, LCP1 ALDH1A1 2351/4885CHRM2 1740/4885ADRA2A 3190/4885
US-10919870-B2 Polymerizable compound and optically anisotropic body ZYX, ZW10, DPY30 ALDH1A1 2807/4885CHRM2 4231/4885ADRA2A 4209/4885
US-20170306233-A1 POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY SMC4, PHOSPHO1, SMCHD1 ALDH1A1 2761/4885CHRM2 4183/4885ADRA2A 4665/4885
US-20180022716-A1 POLYMERIZABLE COMPOUND AND OPTICAL ISOMER SMC4, MAP1LC3C, ZW10 ALDH1A1 3195/4885CHRM2 3729/4885ADRA2A 4519/4885
US-11046889-B2 Polymerizable compound and optically anisotropic body OCIAD1, RCC1, OCIAD2 ALDH1A1 217/4885CHRM2 2552/4885ADRA2A 3770/4885
US-10723952-B2 Polymerizable compound and optically anisotropic body SMC4, SMCHD1, PHOSPHO1 ALDH1A1 2788/4885CHRM2 4160/4885ADRA2A 4641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback