SCHEMBL18874604

SCHEMBL18874604

CCNc1ccc(COC(N)=O)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 4/20 0.46
ADRA2B P18089 1/20 0.46
ADRA2C P18825 1/20 0.46
MAPT P10636 7/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
KMT2A Q03164 5/20 0.39
MEN1 O00255 4/20 0.39
GAA P10253 2/20 0.39
RAB9A P51151 2/20 0.39
KDM4E B2RXH2 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
ALDH1A1 P00352 3/20 0.39
ALOX15 P16050 2/20 0.39
APAF1 O14727 1/20 0.39
USP2 O75604 1/20 0.39
POLB P06746 1/20 0.39
HPGD P15428 1/20 0.39
ALOX12 P18054 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzyl Carbamate SCHEMBL4725135 0.84 RAB9A (0.51) MAPTCA1CA2RAB9AL3MBTL1
SCHEMBL15499765 0.84 ALDH1A1 (0.56) ADRA2AADRA2BADRA2CMAPTCA1
SCHEMBL12173945 0.83 MAPT (0.43) ADRA2AADRA2BADRA2CMAPTCA1
SCHEMBL18752265 0.82 APP (0.45) ADRA2AADRA2BADRA2CMAPTCA1
SCHEMBL22388985 0.81 L3MBTL1 (0.45) MAPTKMT2AMEN1L3MBTL1ALDH1A1
SCHEMBL19154800 0.81 ROCK2 (0.41) ADRA2AADRA2BADRA2CMAPTCA1
SCHEMBL30437401 0.81 KMT2A (0.50) CA2KMT2AMEN1NPSR1L3MBTL1
SCHEMBL7554261 0.80 MEN1 (0.40) MAPTCA1CA2KMT2AMEN1
SCHEMBL17621874 0.80 MAPT (0.40) MAPTCA1CA2KMT2AMEN1
SCHEMBL21120303 0.80 KMT2A (0.43) ADRA2AADRA2BADRA2CMAPTCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230175036-A1 SELF-IMMOLATIVE PROBES FOR ENZYME ACTIVITY DETECTION ENZO LIFE SCIENCES, INC. (US) 2023-06-08 US disclosed
US-20170137863-A1 Self-Immolative Probes for Enzyme Activity Detection ENZO LIFE SCIENCES, INC., C/O ENZO BIOCHEM, INC. (US) 2017-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230175036-A1 SELF-IMMOLATIVE PROBES FOR ENZYME ACTIVITY DETECTION SORD, SI, IMMT ADRA2A 4132/4885ADRA2B 4173/4885ADRA2C 4529/4885
US-20170137863-A1 Self-Immolative Probes for Enzyme Activity Detection MGAM, SI, ENGASE ADRA2A 4328/4885ADRA2B 4389/4885ADRA2C 4465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.