Sugi Predict

Sugi Predict / Compounds / SCHEMBL1889302

SCHEMBL1889302

SCHEMBL1889302

CC(=O)Nc1ccc(O)c(B(O)O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PKM P14618 1/20 0.53
▸ MEN1 O00255 3/20 0.52
▸ MAPT P10636 3/20 0.52
▸ KMT2A Q03164 3/20 0.52
▸ ALDH1A1 P00352 2/20 0.52
▸ CA12 O43570 1/20 0.52
▸ BRD4 O60885 1/20 0.52
▸ NR1I2 O75469 1/20 0.52
▸ CA1 P00915 1/20 0.52
▸ CA2 P00918 1/20 0.52
▸ MB P02144 1/20 0.52
▸ CYP1A1 P04798 1/20 0.52
▸ CA3 P07451 1/20 0.52
▸ CYP3A4 P08684 1/20 0.52
▸ RARG P13631 1/20 0.52
▸ TSHR P16473 1/20 0.52
▸ ALOX5AP P20292 1/20 0.52
▸ CA4 P22748 1/20 0.52
▸ CA7 P43166 1/20 0.52
▸ NR1I3 Q14994 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3323005 0.81 SMN1; SMN2 (0.54) PKMMEN1MAPTKMT2AALDH1A1
SCHEMBL3788150 0.81 HTT (0.48) MEN1MAPTKMT2AALDH1A1CA12
SCHEMBL3192352 0.80 PKM (0.65) PKMMEN1MAPTKMT2AALDH1A1
SCHEMBL8873149 0.80 ALDH1A1 (0.51) MEN1MAPTKMT2AALDH1A1CA12
SCHEMBL4547745 0.80 MEN1 (0.49) MEN1MAPTKMT2AALDH1A1CA12
SCHEMBL16504459 0.79 KDM5A (0.59) PKMMEN1MAPTKMT2AALDH1A1
SCHEMBL29956001 0.78 ALDH1A1 (0.56) PKMMEN1MAPTKMT2AALDH1A1
SCHEMBL3785165 0.78 MEN1 (0.51) PKMMEN1MAPTKMT2AALDH1A1
SCHEMBL2554377 0.78 ALDH1A1 (0.56) PKMMEN1MAPTKMT2AALDH1A1
SCHEMBL18605439 0.77 ALDH1A1 (0.59) MEN1MAPTKMT2AALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115869787-B High-performance anti-biological pollution nanofiltration membrane and preparation and application thereof 华中科技大学 2024-05-14 — — CN claimed
CN-116836121-B Quinazoline compound and preparation method and application thereof 郑州大学 2025-05-02 — — CN disclosed
CN-117946018-A S-triazine LSD1 inhibitor and preparation method and application thereof 郑州大学 2024-04-30 — — CN disclosed
CN-116836121-A Quinazoline compound and preparation method and application thereof 郑州大学 2023-10-03 — — CN disclosed
CN-115869787-A High-performance biological pollution-resistant nanofiltration membrane and preparation and application thereof 华中科技大学 2023-03-31 — — CN disclosed
CN-112654619-B Tricyclic furan substituted piperidine diketone compound 南京明德新药研发有限公司 2022-08-30 — — CN disclosed
CN-111201225-B Coumarin-like ring compound as MEK inhibitor and application thereof 基石药业 2021-11-05 — — CN disclosed
US-11021486-B2 Coumarin-like cyclic compound as MEK inhibitor and use thereof CSTONE PHARMACEUTICALS (KY) 2021-06-01 — — US disclosed
EP-3643308-B1 COUMARIN-LIKE CYCLIC COMPOUND AS MEK INHIBITOR AND USE THEREOF CSTONE PHARMACEUTICALS (KY) 2021-05-19 — — EP disclosed
CN-107098846-B N-acyl sulfonamide FBPase inhibitor, preparation method thereof, pharmaceutical composition and application thereof 中国医学科学院药物研究所 2020-10-09 — — CN disclosed
EP-2535401-A1 Detergent composition comprising soil-release polymers of improved storage stability Dalli-Werke GmbH & Co. KG (DE) 2012-12-19 — — EP disclosed
US-7947691-B2 Cyclic n-hydroxy imides as inhibitors of flap endonuclease and uses thereof ATHERSYS, INC. (US) 2011-05-24 — — US disclosed
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-04-08 — — US disclosed
US-20080287465-A1 Cyclic N-Hydroxy Imides as Inhibitors of Flap Endonuclease and Uses Thereof ATHERSYS, INC. (US) 2008-11-20 — — US disclosed
EP-1914221-A1 PROCESS FOR PRODUCING BIARYL COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-04-23 — — EP disclosed
US-20070232538-A1 Uses of polypeptides TAKEDA PHARMACEUTICAL COMPANY, LTD (JP) 2007-10-04 — — US disclosed
WO-2006014647-A2 CYCLIC N-HYDROXY IMIDES AS INHIBITORS OF FLAP ENDONUCLEASE AND USES THEREOF ATHERSYS, INC. (US) 2006-02-09 — — WO disclosed
WO-2004064774-A2 DNA ENCODING A HUMAN MELANIN CONCENTRATING HORMONE RECEPTOR (MCH1) AND USES THEREOF SYNAPTIC PHARMACEUTICAL CORPORATION (US) 2004-08-05 — — WO disclosed
US-20040053826-A1 Uses of polypeptides TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-03-18 — — US disclosed
EP-1308513-A1 USE OF POLYPEPTIDE Takeda Chemical Industries, Ltd. (JP) 2003-05-07 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11021486-B2 Coumarin-like cyclic compound as MEK inhibitor and use thereof MAP3K11, MAP3K15, MAP3K20 PKM 359/4885MEN1 635/4885MAPT 186/4885
US-20080287465-A1 Cyclic N-Hydroxy Imides as Inhibitors of Flap Endonuclease and Uses Thereof FEN1, UNG, POLH PKM 4301/4885MEN1 3461/4885MAPT 4773/4885
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND NISCH, BLVRB, BBOX1 PKM 3517/4885MEN1 174/4885MAPT 3312/4885
US-20070232538-A1 Uses of polypeptides NPSR1, SCTR, GRPR PKM 4765/4885MEN1 4302/4885MAPT 2628/4885
US-20040053826-A1 Uses of polypeptides NPSR1, SCTR, GRPR PKM 4765/4885MEN1 4302/4885MAPT 2628/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.