Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2550123 | 0.82 | MMP8 (0.53) | MMP8PIN1LMNACYP1A2CYP2D6 | |
| SCHEMBL13379540 | 0.81 | MMP8 (0.46) | MMP8PIN1LMNACYP1A2CYP2D6 | |
| SCHEMBL1696052 | 0.78 | ROCK2 (0.49) | MMP8PIN1LMNAMEN1NPC1 | |
| SCHEMBL8024263 | 0.78 | MMP8 (0.51) | MMP8PIN1LMNACYP1A2CYP2D6 | |
| SCHEMBL7981758 | 0.75 | OPRM1 (0.46) | LMNACYP1A2CYP2D6SMN1; SMN2ALDH1A1 | |
| SCHEMBL1695925 | 0.72 | SLC6A2 (0.47) | MMP8PIN1LMNAMEN1NPC1 | |
| SCHEMBL27831063 | 0.72 | MMP8 (0.41) | MMP8PIN1LMNAMEN1NPC1 | |
| SCHEMBL24661643 | 0.72 | ALDH1A1 (0.50) | MMP8PIN1LMNAMEN1NPC1 | |
| SCHEMBL266419 | 0.71 | MMP8 (0.74) | MMP8PIN1MEN1NPC1KMT2A | |
| SCHEMBL2310025 | 0.71 | LMNA (0.62) | MMP8PIN1LMNACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2328865-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-05-31 | — | — | EP | disclosed |