SCHEMBL18913003

SCHEMBL18913003

O=c1c2ccccc2sn1-c1ccncc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MPI P34949 13/20 0.74
PMM2 O15305 10/20 0.74
PHOSPHO1 Q8TCT1 9/20 0.74
G6PD P11413 6/20 0.74
APOBEC3G Q9HC16 3/20 0.74
KDM4E B2RXH2 3/20 0.74
ALDH1A1 P00352 3/20 0.74
MAPT P10636 3/20 0.74
PKM P14618 3/20 0.74
TDP1 Q9NUW8 3/20 0.74
HPGD P15428 2/20 0.74
ALOX12 P18054 2/20 0.74
CASP3 P42574 2/20 0.74
NPSR1 Q6W5P4 2/20 0.74
HSP90AA1 P07900 1/20 0.74
RAB9A P51151 2/20 0.66
NPC1 O15118 1/20 0.66
TP53 P04637 1/20 0.66
SMN1; SMN2 Q16637 1/20 0.66
KDM5B Q9UGL1 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25763324 0.87 MPI (0.89) MPIPMM2PHOSPHO1G6PDAPOBEC3G
SCHEMBL30562926 0.85 MPI (1.00) MPIPMM2PHOSPHO1G6PDAPOBEC3G
SCHEMBL1898397 0.85 MPI (1.00) MPIPMM2PHOSPHO1G6PDAPOBEC3G
SCHEMBL30738364 0.84 MPI (0.96) MPIPMM2PHOSPHO1G6PDAPOBEC3G
SCHEMBL21032975 0.82 MPI (0.68) MPIPMM2PHOSPHO1G6PDAPOBEC3G
SCHEMBL26964531 0.80 G6PD (0.65) MPIPMM2PHOSPHO1G6PDAPOBEC3G
SCHEMBL21033372 0.79 MPI (0.74) MPIPMM2PHOSPHO1G6PDAPOBEC3G
SCHEMBL1894451 0.79 MPI (1.00) MPIPMM2PHOSPHO1G6PDAPOBEC3G
SCHEMBL29910151 0.79 MPI (1.00) MPIPMM2PHOSPHO1G6PDAPOBEC3G
SCHEMBL1900552 0.79 MPI (0.74) MPIPMM2PHOSPHO1G6PDAPOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11801262-B2 Antibiotic compositions THIOREDOXIN SYSTEMS AB (SE) 2023-10-31 US disclosed
US-20210369696-A1 Use of an N-substituted pyridyl benzisoselazolone compound SHANGHAITECH UNIVERSITY (CN) 2021-12-02 US disclosed
US-11013730-B1 Composition comprising selenazol or thiazalone derivatives and silver and method of treatment therewith THIOREDOXIN SYSTEMS AB (SE) 2021-05-25 US disclosed
US-20200281967-A1 Antibiotic Compositions THIOREDOXIN SYSTEMS AB (SE) 2020-09-10 US disclosed
US-10653717-B2 Antibiotic compositions THIOREDOXIN SYSTEMS AB (SE) 2020-05-19 US disclosed
US-20190307726-A1 PHARMACEUTICAL FORMULATIONS MOLECULAR DEFENSES CORP (US) 2019-10-10 US disclosed
US-20180185410-A1 Antibiotic Compositions THIOREDOXIN SYSTEMS AB (SE) 2018-07-05 US disclosed
WO-2017091737-A1 PHARMACEUTICAL FORMULATIONS Molecular Defenses Corporation (US) 2017-06-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190307726-A1 PHARMACEUTICAL FORMULATIONS GSS, GSR, MGST3 MPI 2231/4885PMM2 4390/4885PHOSPHO1 3253/4885
US-20200281967-A1 Antibiotic Compositions MRPL21, RPS5, MRPS35 MPI 750/4885PMM2 2715/4885PHOSPHO1 329/4885
US-20180185410-A1 Antibiotic Compositions MRPL21, RPS5, MRPS35 MPI 750/4885PMM2 2715/4885PHOSPHO1 329/4885
US-11013730-B1 Composition comprising selenazol or thiazalone derivatives and silver and method of treatment therewith SELENOI, TST, SCLY MPI 1930/4885PMM2 4644/4885PHOSPHO1 2693/4885
US-10653717-B2 Antibiotic compositions MRPL21, RPS5, MRPS35 MPI 750/4885PMM2 2715/4885PHOSPHO1 329/4885
US-20210369696-A1 Use of an N-substituted pyridyl benzisoselazolone compound SARS1, CTSL, ACE2 MPI 691/4885PMM2 1066/4885PHOSPHO1 3333/4885
US-11801262-B2 Antibiotic compositions MRPL21, RPS5, MRPS35 MPI 750/4885PMM2 2715/4885PHOSPHO1 329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.