SCHEMBL1893835

SCHEMBL1893835

COc1ccc(CCCCCCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2/C=C/C(=O)O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1893839 1.00 LTB4R (1.00) LTB4R
SCHEMBL8731919 0.99 LTB4R (1.00) LTB4R
SCHEMBL8073453 0.93 LTB4R (0.87) LTB4R
SCHEMBL8065708 0.93 LTB4R (1.00) LTB4R
SCHEMBL8075661 0.92 LTB4R (0.87) LTB4R
SCHEMBL13696782 0.92 LTB4R (1.00) LTB4R
SCHEMBL8065585 0.92 LTB4R (1.00) LTB4R
SCHEMBL8066017 0.92 LTB4R (1.00) LTB4R
SCHEMBL8862134 0.91 LTB4R (0.84) LTB4R
SCHEMBL8862056 0.91 LTB4R (0.84) LTB4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190216790-A1 Methods for Treating Pruritis THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2019-07-18 US claimed
US-20170333516-A1 PREVENTIVE OR THERAPEUTIC AGENT FOR AGE-RELATED MACULAR DEGENERATION JUNTENDO EDUCATIONAL FOUNDATION (JP) 2017-11-23 US claimed
WO-2001034199-A2 ONCOLYTIC COMBINATIONS FOR THE TREATMENT OF CANCER ELI LILLY AND COMPANY (US) 2001-05-17 WO claimed
US-20250304723-A1 MODIFIED FC PROTEINS COMPRISING SITE-SPECIFIC NON-NATURAL AMINO ACID RESIDUES, CONJUGATES OF THE SAME, METHODS OF THEIR PREPARATION AND METHODS OF THEIR USE SUTRO BIOPHARMA, INC. 2025-10-02 US disclosed
US-20250236674-A9 ANTI-CD74 ANTIBODY CONJUGATES, COMPOSITIONS COMPRISING ANTI CD74 ANTIBODY CONJUGATES AND METHODS OF USING ANTI-CD74 ANTIBODY CONJUGATES SUTRO BIOPHARMA INC (US) 2025-07-24 US disclosed
US-20250236594-A1 MODIFIED AMINO ACIDS SUTRO BIOPHARMA, INC. 2025-07-24 US disclosed
US-20250127793-A1 CONJUGATES OF SURROGATE LIGHT CHAIN CONSTRUCTS REVOPSIS HOLDINGS, LLC 2025-04-24 US disclosed
US-12269801-B2 Modified amino acids SUTRO BIOPHARMA, INC. (US) 2025-04-08 US disclosed
US-20250090676-A1 ANTI-FOLATE RECEPTOR ALPHA ANTIBODY CONJUGATES AND THEIR USES SUTRO BIOPHARMA, INC. 2025-03-20 US disclosed
US-12252552-B2 Modified Fc proteins comprising site-specific non-natural amino acid residues, conjugates of the same, methods of their preparation and methods of their use SUTRO BIOPHARMA, INC. (US) 2025-03-18 US disclosed
US-20250002595-A1 Anti-CD70 Antibody Drug Conjugates AMBRX INC (US) 2025-01-02 US disclosed
US-20170333516-A1 PREVENTIVE OR THERAPEUTIC AGENT FOR AGE-RELATED MACULAR DEGENERATION JUNTENDO EDUCATIONAL FOUNDATION (JP) 2017-11-23 US disclosed
US-20110105959-A1 Novel Methods for Bone Treatment by Modulating an Arachidonic Acid Metabolic or Signaling Pathway ACCELALOX, INC. (US) 2011-05-05 US disclosed
EP-1326605-A4 METHODS FOR INHIBITING PROLIFERATION AND INDUCING APOPTOSIS IN CANCER CELLS UNIV CREIGHTON (US) 2004-03-17 EP disclosed
US-6617345-B1 Cyclooxygenase-2 inhibitor is (5-bromo-2-(4-fluorophenyl )-3-(4-(methylsulfonyl)phey)-thiophene), N-(2-(cyclohexyloxy 4-nitrophenyl)-methanesulfonamide), meloxicam, flosulide or cyclic substituted phenyl sulfones or sulfonamides G.D. SEARLE & CO. 2003-09-09 US disclosed
EP-1326605-A1 METHODS FOR INHIBITING PROLIFERATION AND INDUCING APOPTOSIS IN CANCER CELLS CREIGHTON UNIVERSITY (US) 2003-07-16 EP disclosed
WO-2001085166-A1 METHODS FOR INHIBITING PROLIFERATION AND INDUCING APOPTOSIS IN CANCER CELLS CREIGHTON UNIVERSITY (US) 2001-11-15 WO disclosed
WO-2001034134-A2 ONCOLYTIC COMBINATIONS FOR THE TREATMENT OF CANCER ELI LILLY AND COMPANY (US) 2001-05-17 WO disclosed
WO-2001034133-A2 ONCOLYTIC COMBINATIONS FOR THE TREATMENT OF CANCER ELI LILLY AND COMPANY (US) 2001-05-17 WO disclosed
WO-2001034199-A2 ONCOLYTIC COMBINATIONS FOR THE TREATMENT OF CANCER ELI LILLY AND COMPANY (US) 2001-05-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12252552-B2 Modified Fc proteins comprising site-specific non-natural amino acid residues, conjugates of the same, methods of their preparation and methods of their use FCGR2A, FCGR3B, FCGR1A LTB4R 2559/4885
US-20250090676-A1 ANTI-FOLATE RECEPTOR ALPHA ANTIBODY CONJUGATES AND THEIR USES FOLR1, FOLR2, DHFR LTB4R 1331/4885
US-20250304723-A1 MODIFIED FC PROTEINS COMPRISING SITE-SPECIFIC NON-NATURAL AMINO ACID RESIDUES, CONJUGATES OF THE SAME, METHODS OF THEIR PREPARATION AND METHODS OF THEIR USE FCGR2A, FCGR3B, FCGR1A LTB4R 2559/4885
US-12269801-B2 Modified amino acids PTMS, DNPEP, ANPEP LTB4R 2470/4885
US-20190216790-A1 Methods for Treating Pruritis ITCH, CYSLTR2, CYSLTR1 LTB4R 8/4885
US-20250236594-A1 MODIFIED AMINO ACIDS PTMS, DNPEP, ANPEP LTB4R 2470/4885
US-20170333516-A1 PREVENTIVE OR THERAPEUTIC AGENT FOR AGE-RELATED MACULAR DEGENERATION LTB4R, LTA4H, LTB4R2 LTB4R 1/4885
US-20250236674-A9 ANTI-CD74 ANTIBODY CONJUGATES, COMPOSITIONS COMPRISING ANTI CD74 ANTIBODY CONJUGATES AND METHODS OF USING ANTI-CD74 ANTIBODY CONJUGATES CD74, CD63, CD99 LTB4R 3875/4885
US-20250002595-A1 Anti-CD70 Antibody Drug Conjugates CD63, CD74, CD99 LTB4R 3188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.