Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8226788 | 0.85 | CYP3A4 (0.49) | LMNAMAPTMAPK1CYP1A2CYP3A4 | |
| SCHEMBL1824157 | 0.81 | PGR (0.55) | LMNAMAPTMAPK1KMT2AHSD17B10 | |
| SCHEMBL17002137 | 0.81 | PGR (0.55) | LMNAMAPTMAPK1KMT2AHSD17B10 | |
| SCHEMBL18949121 | 0.80 | L3MBTL1 (0.50) | LMNACYP1A2HDAC3HDAC1HDAC2 | |
| SCHEMBL17198848 | 0.79 | SLC6A2 (0.55) | LMNAMAPTMAPK1CYP1A2CYP3A4 | |
| SCHEMBL19003444 | 0.78 | ALDH1A1 (0.58) | LMNAHDAC3HDAC1HDAC2HSD17B10 | |
| SCHEMBL19880762 | 0.77 | SLC6A4 (0.59) | LMNAMAPTMAPK1CYP1A2CYP3A4 | |
| SCHEMBL27666336 | 0.77 | SLC6A4 (0.59) | LMNAMAPTMAPK1CYP1A2CYP3A4 | |
| SCHEMBL888683 | 0.76 | CYP1A2 (0.55) | LMNAMAPK1CYP1A2CYP3A4MAOA | |
| SCHEMBL7492485 | 0.75 | TAS1R3 (0.58) | LMNAMAPTCYP1A2CYP3A4HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10195189-B2 | 2-phenethenyltetrahydro isoquinolines useful as anti-HIV compounds | Prosetta Antiviral, Inc. (US) | 2019-02-05 | — | — | US | disclosed |
| US-9720140-B2 | Optical film, circularly polarizing plate and organic electroluminescent display device | Konica Minolta, Inc. (JP) | 2017-08-01 | — | — | US | disclosed |
| US-9676802-B2 | Hepatitis C virus inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2017-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10195189-B2 | 2-phenethenyltetrahydro isoquinolines useful as anti-HIV compounds | MAVS, EIF2AK2, POLRMT | LMNA 3070/4885MAPT 1106/4885MAPK1 3695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.