Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24221611 | 0.85 | LMNA (0.48) | CYP2D6KDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL18949188 | 0.85 | LMNA (0.55) | CYP3A4CYP1A2MAOAMAOBPTGS2 | |
| SCHEMBL18782788 | 0.82 | NAPRT (0.46) | CYP3A4CYP1A2MAOAMAOBPTGS2 | |
| SCHEMBL14705760 | 0.80 | MAOA (0.41) | CYP3A4CYP1A2MAOAMAOBPTGS2 | |
| SCHEMBL10489465 | 0.79 | PGR (0.58) | KMT2ALMNAMAPTMAPK1HPGD | |
| SCHEMBL12955855 | 0.79 | KDM4E (0.48) | CYP2D6KDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL2128162 | 0.79 | PGR (0.58) | KMT2ALMNAMAPTMAPK1HPGD | |
| SCHEMBL888683 | 0.79 | CYP1A2 (0.55) | CYP3A4CYP1A2MAOAMAOBPTGS2 | |
| SCHEMBL4424991 | 0.78 | NAPRT (0.48) | CYP3A4CYP1A2MAOAMAOBPTGS2 | |
| SCHEMBL13845395 | 0.78 | ALDH1A1 (0.52) | KMT2ANPSR1LMNAALDH1A1PLOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11407732-B1 | Tricyclic degraders of Ikaros and Aiolos | C4 THERAPEUTICS, INC. (US) | 2022-08-09 | — | — | US | disclosed |
| US-20190111044-A1 | 2-PHENETHENYLTETRAHYDRO ISOQUINOLINES USEFUL AS ANTI-HIV COMPOUNDS | Prosetta Antiviral, Inc. | 2019-04-18 | — | — | US | disclosed |
| US-7452672-B2 | Methods of analyzing polynucleotides employing energy transfer dyes | APPLIED BIOSYSTEMS INC. (US) | 2008-11-18 | — | — | US | disclosed |
| WO-2008033460-A2 | TREATING PAIN, DIABETES, AND LIPID METABOLISM DISORDERS | SCHERING CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |
| US-20070154926-A1 | Linkers for donor dyes to acceptor dyes for energy transfer between dyes with fluorescence | APPLERA CORPORATION (US) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190111044-A1 | 2-PHENETHENYLTETRAHYDRO ISOQUINOLINES USEFUL AS ANTI-HIV COMPOUNDS | MAVS, EIF2AK2, POLRMT | CYP3A4 823/4885CYP1A2 1713/4885MAOA 3442/4885 |
| US-11407732-B1 | Tricyclic degraders of Ikaros and Aiolos | CRBN, IKZF1, IKZF3 | CYP3A4 1961/4885CYP1A2 2707/4885MAOA 1724/4885 |
| US-20070154926-A1 | Linkers for donor dyes to acceptor dyes for energy transfer between dyes with fluorescence | SLC25A21, RPS28, ZCCHC8 | CYP3A4 3376/4885CYP1A2 2761/4885MAOA 1835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.