Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL190469 | 0.86 | NOTUM (0.66) | NOTUMRAB9AL3MBTL1NPC1SMN1; SMN2 | |
| SCHEMBL190599 | 0.86 | RAB9A (0.64) | RAB9AL3MBTL1NPC1SMN1; SMN2TDP1 | |
| SCHEMBL190361 | 0.84 | RAB9A (0.54) | NOTUMRAB9AL3MBTL1NPC1SMN1; SMN2 | |
| SCHEMBL189513 | 0.83 | RAB9A (0.53) | NOTUMRAB9AL3MBTL1NPC1SMN1; SMN2 | |
| SCHEMBL190343 | 0.83 | RAB9A (0.62) | RAB9AL3MBTL1NPC1SMN1; SMN2TDP1 | |
| SCHEMBL14707191 | 0.83 | RAB9A (0.61) | RAB9AL3MBTL1NPC1SMN1; SMN2TDP1 | |
| SCHEMBL189840 | 0.83 | RAB9A (0.59) | RAB9AL3MBTL1NPC1SMN1; SMN2TDP1 | |
| SCHEMBL189312 | 0.81 | RAB9A (0.54) | NOTUMRAB9AL3MBTL1NPC1SMN1; SMN2 | |
| SCHEMBL189684 | 0.81 | RAB9A (0.54) | NOTUMRAB9AL3MBTL1NPC1SMN1; SMN2 | |
| SCHEMBL189501 | 0.81 | RAB9A (0.59) | RAB9AL3MBTL1NPC1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2917188-B1 | SOLID DISPERSIONS OF INSOLUBLE DRUG AND PREPARATION METHOD THEREOF | SK BIOPHARMACEUTICALS CO LTD (KR) | 2018-08-01 | — | — | EP | disclosed |
| US-9724335-B2 | Solid dispersions of insoluble drug and preparation method thereof | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2017-08-08 | — | — | US | disclosed |
| US-20170105973-A1 | SOLID DISPERSIONS OF INSOLUBLE DRUG AND PREPARATION METHOD THEREOF | SK BIOPHARMACEUTICALS CO., LTD. | 2017-04-20 | — | — | US | disclosed |
| US-9566268-B2 | Solid dispersions of insoluble drug and preparation method thereof | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2017-02-14 | — | — | US | disclosed |
| US-20160346258-A1 | SOLID DISPERSIONS OF INSOLUBLE DRUG AND PREPARATION METHOD THEREOF | SK BIOPHARMACEUTICALS CO., LTD. | 2016-12-01 | — | — | US | disclosed |
| US-9439970-B2 | Solid dispersions of insoluble drug and preparation method thereof | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2016-09-13 | — | — | US | disclosed |
| US-9290464-B2 | Pharmaceutical composition for inhibiting apoptosis of neuron or neurodegeneration | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2016-03-22 | — | — | US | disclosed |
| EP-2401263-B1 | SUBSTITUTED AZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVES, AND METHOD FOR TREATING PARKINSON'S DISEASE USING THE SAME | SK BIOPHARMACEUTICALS CO LTD (KR) | 2016-02-17 | — | — | EP | disclosed |
| US-20150283243-A1 | SOLID DISPERSIONS OF INSOLUBLE DRUG AND PREPARATION METHOD THEREOF | SK BIOPHARMACEUTICALS CO., LTD. a corporation | 2015-10-08 | — | — | US | disclosed |
| EP-2917188-A1 | SOLID DISPERSIONS OF INSOLUBLE DRUG AND PREPARATION METHOD THEREOF | SK Biopharmaceuticals Co., LTD (KR) | 2015-09-16 | — | — | EP | disclosed |
| US-8828992-B2 | Substituted azole derivatives, pharmaceutical composition containing the derivatives, and method for treating Parkinson's disease using the same | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2014-09-09 | — | — | US | disclosed |
| WO-2014073889-A1 | SOLID DISPERSIONS OF INSOLUBLE DRUG AND PREPARATION METHOD THEREOF | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2014-05-15 | — | — | WO | disclosed |
| EP-2566475-A2 | PHARMACEUTICAL COMPOSITION FOR INHIBITING APOPTOSIS OF NEURON OR NEURODEGENERATION | SK Biopharmaceuticals Co., Ltd. (KR) | 2013-03-13 | — | — | EP | disclosed |
| US-20130046001-A1 | PHARMACEUTICAL COMPOSITION FOR INHIBITING APOPTOSIS OF NEURON OR NEURODEGENERATION | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2013-02-21 | — | — | US | disclosed |
| EP-2401263-A2 | SUBSTITUTED AZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVES, AND METHOD FOR TREATING PARKINSON'S DISEASE USING THE SAME | SK Biopharmaceuticals Co., Ltd. (KR) | 2012-01-04 | — | — | EP | disclosed |
| US-20110301150-A1 | SUBSTITUTED AZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVES, AND METHOD FOR TREATING PARKINSON'S DISEASE USING THE SAME | SK BIOPHARMACEUTICALS CO., LTD. | 2011-12-08 | — | — | US | disclosed |
| WO-2011139079-A2 | PHARMACEUTICAL COMPOSITION FOR INHIBITING APOPTOSIS OF NEURON OR NEURODEGENERATION | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2011-11-10 | — | — | WO | disclosed |
| WO-2010098600-A2 | SUBSTITUTED AZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVES, AND METHOD FOR TREATING PARKINSON'S DISEASE USING THE SAME | SK HOLDINGS CO., LTD. (KR) | 2010-09-02 | — | — | WO | disclosed |
| US-20080045580-A1 | Novel Isoxazole Compounds Having Ppar Agonist Activity | DR REDDY'S LABORATORIES LIMITED (IN) | 2008-02-21 | — | — | US | disclosed |
| WO-2006042245-A1 | NOVEL ISOXAZOLE COMPOUNDS HAVING PPAR AGONIST ACTIVITY | DR. REDDY'S LABORATORIES LTD. (IN) | 2006-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160346258-A1 | SOLID DISPERSIONS OF INSOLUBLE DRUG AND PREPARATION METHOD THEREOF | SI, CYP3A7, ABCG2 | NOTUM 828/4885RAB9A 1475/4885L3MBTL1 4553/4885 |
| US-20110301150-A1 | SUBSTITUTED AZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITION CONTAINING THE DERIVATIVES, AND METHOD FOR TREATING PARKINSON'S DISEASE USING THE SAME | MAOB, MAOA, PARK7 | NOTUM 1260/4885RAB9A 1245/4885L3MBTL1 4729/4885 |
| US-20080045580-A1 | Novel Isoxazole Compounds Having Ppar Agonist Activity | PPARG, PPARA, PPARD | NOTUM 1325/4885RAB9A 2782/4885L3MBTL1 4836/4885 |
| US-20170105973-A1 | SOLID DISPERSIONS OF INSOLUBLE DRUG AND PREPARATION METHOD THEREOF | SI, CYP3A7, ABCG2 | NOTUM 828/4885RAB9A 1475/4885L3MBTL1 4553/4885 |
| US-20130046001-A1 | PHARMACEUTICAL COMPOSITION FOR INHIBITING APOPTOSIS OF NEURON OR NEURODEGENERATION | BAX, NLN, CASP3 | NOTUM 2486/4885RAB9A 2788/4885L3MBTL1 2556/4885 |
| US-20150283243-A1 | SOLID DISPERSIONS OF INSOLUBLE DRUG AND PREPARATION METHOD THEREOF | SI, ABCG2, CYP3A7 | NOTUM 930/4885RAB9A 1774/4885L3MBTL1 3702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.