Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | LOX | P28300 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13819913 | 0.80 | NUDT1 (0.43) | NUDT1LOXLOXL2 | |
| SCHEMBL13028821 | 0.76 | LMNA (0.42) | — | |
| SCHEMBL18994387 | 0.75 | HTR1A (0.31) | — | |
| SCHEMBL13819909 | 0.68 | RIPK1 (0.47) | NUDT1 | |
| SCHEMBL22905267 | 0.68 | ALOX5AP (0.33) | — | |
| SCHEMBL14552441 | 0.63 | MAPT (0.39) | NUDT1 | |
| SCHEMBL21324866 | 0.63 | NUDT1 (0.34) | NUDT1 | |
| SCHEMBL2632841 | 0.63 | TAAR1 (0.41) | NUDT1LOXLOXL2 | |
| SCHEMBL16211775 | 0.63 | LMNA (0.39) | — | |
| SCHEMBL28020306 | 0.62 | HTR7 (0.37) | NUDT1LOXLOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682998-B2 | Fused heterocyclic compounds as ion channel modulators | GILEAD SCIENCES, INC. (US) | 2017-06-20 | — | — | US | disclosed |