Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 9/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | STK17B | O94768 | 2/20 | 0.40 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.40 |
| ▸ | SYK | P43405 | 3/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | ITK | Q08881 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18995069 | 0.88 | ULK1 (0.44) | STK17BSTK17ASYK | |
| SCHEMBL19527725 | 0.88 | TNIK (0.39) | STK17ASYKEGFRITKSCN9A | |
| SCHEMBL19527748 | 0.86 | TBK1 (0.37) | SYKEGFRITKSCN9A | |
| SCHEMBL18995121 | 0.85 | NPC1 (0.47) | — | |
| SCHEMBL19836644 | 0.85 | NPC1 (0.49) | STK17BSTK17ASYKEGFR | |
| SCHEMBL18995059 | 0.83 | EGFR (0.41) | BCL6STK17BSTK17ASYKNCOR2 | |
| SCHEMBL18995005 | 0.81 | BCL6 (0.41) | BCL6MAPK1STK17BSTK17ASYK | |
| SCHEMBL29352285 | 0.80 | BCL6 (0.61) | BCL6STK17BSTK17ASYKNCOR2 | |
| SCHEMBL18995042 | 0.80 | BCL6 (0.42) | BCL6MAPK1STK17BSTK17ASYK | |
| SCHEMBL19836663 | 0.77 | BCL6 (0.43) | BCL6MAPK1STK17BSTK17ASYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682976-B2 | Protein kinase C inhibitors and uses thereof | RIGEL PHARMACEUTICALS, INC. (US) | 2017-06-20 | — | — | US | disclosed |