SCHEMBL189971

SCHEMBL189971

CC1(C)OB(c2cnc(N)nc2)OC1(C)C

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LPL P06858 10/20 0.41
LIPG Q9Y5X9 10/20 0.41
PDGFRB P09619 1/20 0.39
KDR P35968 1/20 0.39
FFAR1 O14842 1/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 2/20 0.39
CA12 O43570 1/20 0.39
CA3 P07451 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA7 P43166 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
DGAT1 O75907 2/20 0.38
F11 P03951 1/20 0.38
AAK1 Q2M2I8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Boric Acid SCHEMBL31176956 0.93 PDGFRB (0.39) LPLLIPGPDGFRBKDRFFAR1
SCHEMBL2872042 0.85 PDGFRB (0.43) LPLLIPGPDGFRBKDRFFAR1
SCHEMBL12537248 0.84 PDGFRB (0.30) PDGFRBKDR
SCHEMBL15916971 0.82 DGAT1 (0.53) LPLLIPGPDGFRBKDRCA1
SCHEMBL1284338 0.81 LPL (0.42) LPLLIPGFFAR1CA1CA2
SCHEMBL28088657 0.81 PDGFRB (0.30) PDGFRBKDR
SCHEMBL15936842 0.79 FEN1 (0.48) LPLLIPGPDGFRBKDRAAK1
SCHEMBL20315296 0.79 FFAR1 (0.42) LPLLIPGPDGFRBKDRFFAR1
SCHEMBL20137083 0.79 LPL (0.48) LPLLIPGFFAR1CA1CA2
SCHEMBL28990423 0.79 LPL (0.41) LPLLIPGFFAR1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1085 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4326276-A1 IMPROVED PROCESS FOR THE PREPARATION OF 7-(MORPHOLINYL)-2-(N-PIPERAZINYL)METHYLTHIENO[2, 3-C]PYRIDINE DERIVATIVES Natco Pharma Ltd (IN) 2024-02-28 EP claimed
WO-2022224267-A1 IMPROVED PROCESS FOR THE PREPARATION OF 7-(MORPHOLINYL)-2-(N-PIPERAZINYL)METHYLTHIENO[2, 3-C]PYRIDINE DERIVATIVES NATCO PHARMA LIMITED (IN) 2022-10-27 WO claimed
US-12637450-B2 Tri-substituted aryl and heteroaryl derivatives as modulators of PI3-kinase and autophagy pathways GLOBAL CANCER TECHNOLOGY INC. (US) 2026-05-26 US disclosed
US-12630529-B2 GCN2 modulator compounds Alesta Therapeutics BV (NL) 2026-05-19 US disclosed
US-20260125395-A1 PROCESS FOR THE PREPARATION OF TRICYCLIC PI3K INHIBITOR COMPOUNDS AND METHODS FOR USING THE SAME FOR THE TREATMENT OF CANCER GENENTECH INC (US) 2026-05-07 US disclosed
EP-4713095-A1 COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS Chengdu Anticancer Bioscience, Ltd. (CN) 2026-03-25 EP disclosed
EP-4415816-B1 PYRROLO[2,1-F][1,2,4]TRIAZINES DERIVATIVES AS INHIBITORS OF DYRK1A BIOSPLICE THERAPEUTICS INC (US) 2026-03-18 EP disclosed
US-20250388599-A1 TRICYCLIC PI3K INHIBITOR COMPOUNDS AND METHODS OF USE GENENTECH INC (US) 2025-12-25 US disclosed
US-20250361236-A9 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS GILEAD SCIENCES INC (US) 2025-11-27 US disclosed
EP-4647076-A2 THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE Les Laboratoires Servier (FR) 2025-11-12 EP disclosed
US-20250325550-A1 HETEROCYCLYLAMINES AS PI3K INHIBITORS INCYTE CORP (US) 2025-10-23 US disclosed
WO-2007084786-A1 PYRIMIDINE DERIVATIVES USED AS PI-3 KINASE INHIBITORS NOVARTIS AG (CH) 2007-07-26 WO disclosed
WO-2007084786-A1 PYRIMIDINE DERIVATIVES USED AS PI-3 KINASE INHIBITORS NOVARTIS AG (CH) 2007-07-26 WO disclosed
EP-1202955-A4 1,4-SUBSTITUTED 4,4-DIARYL CYCLOHEXANES SMITHKLINE BEECHAM CORP (US) 2004-02-11 EP disclosed
US-6518306-B1 PDE4 inhibitors particularly in regards to treating allergic and inflammatory diseases SMITHKLINE BEECHAM CORPORATION 2003-02-11 US disclosed
US-6410728-B1 BACTERICIDES; PSORIASIS; ANTIARTHRITIC AGENTS; TREATING TOXICITY DUE TO CHEMOTHERAPY; OBESITY; ANTIBIOTIC-RESISTANT STAPHYLOCOCCUS, MORAXELLA, ENTEROCOCCUS AND STREPTOCOCCUS; GRAMPOSITIVE BACTERIA ABBOTT LABORATORIES 2002-06-25 US disclosed
EP-1202955-A2 1,4-SUBSTITUTED 4,4-DIARYL CYCLOHEXANES SmithKline Beecham Corporation (US) 2002-05-08 EP disclosed
US-20020045625-A1 OXAZOLIDINONE CHEMOTHERAPEUTIC AGENTS ABBOTT LABORATORIES 2002-04-18 US disclosed
WO-2002018353-A2 OXAZOLIDINONE CHEMOTHERAPEUTIC AGENTS ABBOTT LABORATORIES (US) 2002-03-07 WO disclosed
WO-2001010385-A2 1,4-SUBSTITUTED 4,4-DIARYL CYCLOHEXANES SMITHKLINE BEECHAM CORPORATION (US) 2001-02-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630529-B2 GCN2 modulator compounds NR3C1, GCN1, EIF2AK4 LPL 1991/4885LIPG 3450/4885PDGFRB 3811/4885
US-20250325550-A1 HETEROCYCLYLAMINES AS PI3K INHIBITORS PIK3CA, PIK3CD, PIK3CB LPL 3855/4885LIPG 2672/4885PDGFRB 389/4885
US-20260125395-A1 PROCESS FOR THE PREPARATION OF TRICYCLIC PI3K INHIBITOR COMPOUNDS AND METHODS FOR USING THE SAME FOR THE TREATMENT OF CANCER PIK3C2B, PIK3C2A, PIK3CA LPL 2951/4885LIPG 3375/4885PDGFRB 467/4885
US-12637450-B2 Tri-substituted aryl and heteroaryl derivatives as modulators of PI3-kinase and autophagy pathways PIK3R4, PIK3R1, ATG7 LPL 1524/4885LIPG 1661/4885PDGFRB 616/4885
US-20250361236-A9 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS DGKG, DGKB, DGKK LPL 559/4885LIPG 215/4885PDGFRB 1157/4885
US-20020045625-A1 OXAZOLIDINONE CHEMOTHERAPEUTIC AGENTS OXA1L, TK1, PDCD1 LPL 4527/4885LIPG 4683/4885PDGFRB 3623/4885
US-20250388599-A1 TRICYCLIC PI3K INHIBITOR COMPOUNDS AND METHODS OF USE PIK3C2B, PIK3C2A, PIK3R1 LPL 3263/4885LIPG 1906/4885PDGFRB 657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.