Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003357 | 0.84 | EGFR (0.42) | RAB9ASMN1; SMN2NPC1LMNAMAPT | |
| SCHEMBL19003251 | 0.76 | EGFR (0.68) | RAB9ASMN1; SMN2NPC1LMNAMAPT | |
| SCHEMBL19003261 | 0.75 | MMP1 (0.59) | RAB9ASMN1; SMN2NPC1LMNAMAPT | |
| SCHEMBL18985272 | 0.73 | MAOB (0.63) | RAB9ASMN1; SMN2NPC1LMNAMAPT | |
| SCHEMBL19003464 | 0.72 | EGFR (0.53) | RAB9ASMN1; SMN2NPC1LMNAMAPT | |
| SCHEMBL19003354 | 0.70 | MMP1 (0.62) | RAB9ASMN1; SMN2NPC1LMNAMAPT | |
| SCHEMBL19003255 | 0.70 | EGFR (0.47) | RAB9ASMN1; SMN2NPC1LMNAMAPT | |
| SCHEMBL19003356 | 0.70 | TRPV1 (0.49) | RAB9ASMN1; SMN2NPC1LMNAMAPT | |
| SCHEMBL19003250 | 0.69 | MAPT (0.51) | RAB9ASMN1; SMN2NPC1LMNAMAPT | |
| SCHEMBL19003274 | 0.69 | MMP1 (0.58) | RAB9ASMN1; SMN2NPC1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |