Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | KCNJ6 | P48051 | 8/20 | 0.51 |
| ▸ | KCNJ3 | P48549 | 8/20 | 0.51 |
| ▸ | KCNJ5 | P48544 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003350 | 0.76 | ALDH1A1 (0.47) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19003264 | 0.76 | NR4A1 (0.56) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19003250 | 0.74 | MAPT (0.51) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19003252 | 0.73 | RAB9A (0.53) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19003464 | 0.73 | EGFR (0.53) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19003347 | 0.73 | CYP1A2 (0.54) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19003248 | 0.72 | LMNA (0.56) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18985272 | 0.72 | MAOB (0.63) | LMNANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL19003274 | 0.71 | MMP1 (0.58) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19003254 | 0.71 | EGFR (0.53) | ALDH1A1LMNANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |