Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 11/20 | 0.40 |
| ▸ | NPC1 | O15118 | 9/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003363 | 0.84 | RAB9A (0.52) | EGFRRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL19003356 | 0.74 | TRPV1 (0.49) | EGFRRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL19003261 | 0.72 | MMP1 (0.59) | EGFRRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL19003464 | 0.71 | EGFR (0.53) | EGFRRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL19003251 | 0.70 | EGFR (0.68) | EGFRRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL19003255 | 0.69 | EGFR (0.47) | EGFRRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL19003250 | 0.69 | MAPT (0.51) | EGFRRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL19003274 | 0.68 | MMP1 (0.58) | EGFRRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL19003362 | 0.68 | RAB9A (0.46) | EGFRRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL19003254 | 0.68 | EGFR (0.53) | EGFRRAB9ANPC1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |