SCHEMBL19019666

SCHEMBL19019666

CCOC(=O)c1nn(-c2cccnc2)cc1O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 13/20 0.74
RAB9A P51151 10/20 0.74
ALDH1A1 P00352 9/20 0.67
SMN1; SMN2 Q16637 8/20 0.67
KDM4E B2RXH2 6/20 0.64
LMNA P02545 1/20 0.64
NPSR1 Q6W5P4 3/20 0.62
CYP1A2 P05177 1/20 0.62
CYP2D6 P10635 1/20 0.62
CYP2C19 P33261 1/20 0.62
MAPT P10636 2/20 0.59
TP53 P04637 3/20 0.56
HSD17B10 Q99714 3/20 0.56
HPGD P15428 2/20 0.56
ALOX15 P16050 2/20 0.56
GLA P06280 2/20 0.47
MAPK1 P28482 2/20 0.47
POLB P06746 1/20 0.47
NFKB1 P19838 1/20 0.46
NFKB2 Q00653 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19875205 0.86 NPC1 (0.55) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL23234405 0.86 NPC1 (0.55) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL24505868 0.85 NPC1 (0.54) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL23234389 0.85 NPC1 (0.54) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL23234386 0.82 NPC1 (0.51) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL19875273 0.82 MAPT (0.54) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL1680448 0.81 NPC1 (0.66) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL30754194 0.81 NPC1 (0.52) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL23234383 0.81 NPC1 (0.52) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL21799397 0.80 NPC1 (0.54) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12302903-B2 Oxazepinone derivative, agricultural/horticultural insecticide containing the same, and method for using the same NIHON NOHYAKU CO., LTD. (JP) 2025-05-20 US disclosed
US-12258326-B2 Pyrazole derivative and harmful organism-controlling agent KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2025-03-25 US disclosed
US-20240254102-A1 PYRAZOLE DERIVATIVE AND HARMFUL ORGANISM-CONTROLLING AGENT KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2024-08-01 US disclosed
US-11993578-B2 Pyrazole-3-carboxylic acid amide derivative and pest control agent KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2024-05-28 US disclosed
US-11964957-B2 Pyrazole derivative and harmful organism-controlling agent KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2024-04-23 US disclosed
EP-3808738-B1 PYRAZOLE DERIVATIVE AND HARMFUL ORGANISM-CONTROLLING AGENT KUMIAI CHEMICAL INDUSTRY CO (JP) 2024-04-17 EP disclosed
CN-112236421-B Pyrazole derivatives and pest control agents 组合化学工业株式会社 2023-12-26 CN disclosed
CN-114144419-B Oxazepine derivatives and agrohorticultural pesticides containing the same and methods of use thereof 日本农药株式会社 2023-11-21 CN disclosed
CN-110612295-B Pyrazole-3-carboxylic acid amide derivative and pest control agent 组合化学工业株式会社 2023-07-14 CN disclosed
EP-3623365-B1 PYRAZOLE-3-CARBOXYLIC ACID AMIDE DERIVATIVE AND PEST CONTROL AGENT KUMIAI CHEMICAL INDUSTRY CO (JP) 2023-01-04 EP disclosed
CN-112236421-A Pyrazole derivative and pest control agent 组合化学工业株式会社 2021-01-15 CN disclosed
US-20200199096-A1 PYRAZOLE-3-CARBOXYLIC ACID AMIDE DERIVATIVE AND PEST CONTROL AGENT KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2020-06-25 US disclosed
EP-3623365-A1 PYRAZOLE-3-CARBOXYLIC ACID AMIDE DERIVATIVE AND PEST CONTROL AGENT Kumiai Chemical Industry Co., Ltd. (JP) 2020-03-18 EP disclosed
CN-110612295-A Pyrazole-3-carboxylic acid amide derivative and pest control agent 组合化学工业株式会社 2019-12-24 CN disclosed
EP-3184528-B1 OXAZEPINE COMPOUND, PESTICIDE FOR AGRICULTURAL AND HORTICULTURAL USE WHICH CONTAINS SAID COMPOUND AS ACTIVE INGREDIENT, AND METHOD FOR USING SAID PESTICIDE FOR AGRICULTURAL AND HORTICULTURAL USE NIHON NOHYAKU CO LTD (JP) 2019-06-19 EP disclosed
US-10100061-B2 Oxazepine compound and agricultural/horticultural insecticide containing said compound as active ingredient, and method for using the same NIHON NOHYAKU CO., LTD. (JP) 2018-10-16 US disclosed
US-20170260199-A1 OXAZEPINE COMPOUND AND AGRICULTURAL/HORTICULTURAL INSECTICIDE CONTAINING SAID COMPOUND AS ACTIVE INGREDIENT, AND METHOD FOR USING THE SAME NIHON NOHYAKU CO., LTD. (JP) 2017-09-14 US disclosed
US-20170260199-A1 OXAZEPINE COMPOUND AND AGRICULTURAL/HORTICULTURAL INSECTICIDE CONTAINING SAID COMPOUND AS ACTIVE INGREDIENT, AND METHOD FOR USING THE SAME NIHON NOHYAKU CO., LTD. (JP) 2017-09-14 US disclosed
US-20170260199-A1 OXAZEPINE COMPOUND AND AGRICULTURAL/HORTICULTURAL INSECTICIDE CONTAINING SAID COMPOUND AS ACTIVE INGREDIENT, AND METHOD FOR USING THE SAME NIHON NOHYAKU CO., LTD. (JP) 2017-09-14 US disclosed
EP-3184528-A1 OXAZEPINE COMPOUND, PESTICIDE FOR AGRICULTURAL AND HORTICULTURAL USE WHICH CONTAINS SAID COMPOUND AS ACTIVE INGREDIENT, AND METHOD FOR USING SAID PESTICIDE FOR AGRICULTURAL AND HORTICULTURAL USE Nihon Nohyaku Co., Ltd. (JP) 2017-06-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10100061-B2 Oxazepine compound and agricultural/horticultural insecticide containing said compound as active ingredient, and method for using the same OXSR1, OXER1, KCNH1 NPC1 3346/4885RAB9A 2905/4885ALDH1A1 1348/4885
US-11964957-B2 Pyrazole derivative and harmful organism-controlling agent L3MBTL3, L3MBTL1, L3MBTL4 NPC1 4813/4885RAB9A 458/4885ALDH1A1 1266/4885
US-20200199096-A1 PYRAZOLE-3-CARBOXYLIC ACID AMIDE DERIVATIVE AND PEST CONTROL AGENT H1-3, HDAC3, H1-0 NPC1 3658/4885RAB9A 166/4885ALDH1A1 810/4885
US-20240254102-A1 PYRAZOLE DERIVATIVE AND HARMFUL ORGANISM-CONTROLLING AGENT L3MBTL3, PIR, PDK3 NPC1 4807/4885RAB9A 943/4885ALDH1A1 960/4885
US-20170260199-A1 OXAZEPINE COMPOUND AND AGRICULTURAL/HORTICULTURAL INSECTICIDE CONTAINING SAID COMPOUND AS ACTIVE INGREDIENT, AND METHOD FOR USING THE SAME OXSR1, OXER1, KCNH1 NPC1 3346/4885RAB9A 2905/4885ALDH1A1 1348/4885
US-11993578-B2 Pyrazole-3-carboxylic acid amide derivative and pest control agent H1-3, HDAC3, H1-0 NPC1 3658/4885RAB9A 166/4885ALDH1A1 810/4885
US-12302903-B2 Oxazepinone derivative, agricultural/horticultural insecticide containing the same, and method for using the same OXER1, OXSR1, CYP4A22 NPC1 2888/4885RAB9A 4259/4885ALDH1A1 261/4885
US-12258326-B2 Pyrazole derivative and harmful organism-controlling agent L3MBTL3, PIR, PDK3 NPC1 4807/4885RAB9A 943/4885ALDH1A1 960/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.