Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19061872 | 0.90 | MAPK1 (0.41) | ALDH1A1HTTMAPTCYP1A2CYP2D6 | |
| SCHEMBL19019863 | 0.87 | MGAM (0.41) | ALDH1A1GFERKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL19019923 | 0.87 | GAA (0.43) | ALDH1A1GFERKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL22263126 | 0.85 | HTT (0.41) | ALDH1A1HTTKMT2AMAPTCYP1A2 | |
| SCHEMBL19061438 | 0.83 | ALDH1A1 (0.43) | ALDH1A1HTTKMT2ARAB9AKDM4E | |
| SCHEMBL19062037 | 0.81 | METAP2 (0.43) | ALDH1A1GFERKMT2AMAPTKDM4E | |
| SCHEMBL20920814 | 0.80 | SOS1 (0.39) | GFERKMT2AMAPTCYP1A2CYP2D6 | |
| SCHEMBL20917965 | 0.80 | MAPK1 (0.41) | ALDH1A1GFERKMT2AMAPTCYP1A2 | |
| SCHEMBL14286352 | 0.80 | OPRK1 (0.48) | KMT2AMAPTCYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL19019925 | 0.79 | TRPV6 (0.43) | ALDH1A1HTTCYP1A2CYP2D6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3184514-A1 | AUTOPHAGY INHIBITORS | Deutsches Krebsforschungszentrum (DE) | 2017-06-28 | — | — | EP | disclosed |