Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 9/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CCR1 | P32246 | 3/20 | 0.43 |
| ▸ | CCR5 | P51681 | 3/20 | 0.43 |
| ▸ | CCR8 | P51685 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19056869 | 0.79 | SLC40A1 (0.43) | SLC40A1LMNACCR1CCR5CCR8 | |
| SCHEMBL19056900 | 0.79 | CCR1 (0.42) | SLC40A1CCR1CCR5 | |
| SCHEMBL21358576 | 0.78 | SLC40A1 (0.44) | SLC40A1LMNACCR1CCR5CCR8 | |
| SCHEMBL19056880 | 0.78 | SLC40A1 (0.39) | SLC40A1LMNACCR1CCR5CCR8 | |
| SCHEMBL21358807 | 0.77 | SLC40A1 (0.43) | SLC40A1LMNACCR1CCR5CCR8 | |
| SCHEMBL6740937 | 0.75 | ADRA2A (0.38) | TSHRKDM4EMAPTCYP2D6NFKB1 | |
| SCHEMBL19511078 | 0.75 | ALDH1A1 (0.35) | TSHRALOX15KDM4EGFER | |
| SCHEMBL13154645 | 0.74 | LMNA (0.52) | SLC40A1LMNACCR1CCR5CCR8 | |
| SCHEMBL9138052 | 0.72 | SLC40A1 (0.49) | SLC40A1LMNACCR1CCR5CCR8 | |
| SCHEMBL19056873 | 0.71 | PDE10A (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106573941-B | Novel 4th group transition metal compound and application thereof | 韩华化学株式会社 | 2019-07-12 | — | — | CN | disclosed |
| EP-3187499-B1 | NOVEL GROUP 4 TRANSITION METAL COMPOUND AND USE THEREOF | HANWHA CHEMICAL CORP (KR) | 2019-04-24 | — | — | EP | disclosed |
| US-10160775-B2 | Group 4 transition metal compound and use thereof | HANWHA CHEMICAL CORPORATION (KR) | 2018-12-25 | — | — | US | disclosed |
| US-20170233415-A1 | NOVEL GROUP 4 TRANSITION METAL COMPOUND AND USE THEREOF | HANWHA CHEMICAL CORPORATION (KR) | 2017-08-17 | — | — | US | disclosed |
| EP-3187499-A1 | NOVEL GROUP 4 TRANSITION METAL COMPOUND AND USE THEREOF | Hanwha Chemical Corporation (KR) | 2017-07-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233415-A1 | NOVEL GROUP 4 TRANSITION METAL COMPOUND AND USE THEREOF | TRPV4, TRPM4, MORF4L1 | SLC40A1 678/4885LMNA 4374/4885CCR1 2517/4885 |
| US-10160775-B2 | Group 4 transition metal compound and use thereof | TRPV4, TRPM4, MORF4L1 | SLC40A1 794/4885LMNA 4174/4885CCR1 2202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.