Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19062034 | 0.89 | GFER (0.44) | HSD17B10ALDH1A1KDM4ETDP1KMT2A | |
| SCHEMBL19061459 | 0.88 | RAB9A (0.46) | HSD17B10ALDH1A1KDM4ECHRNB2CHRNA4 | |
| SCHEMBL19061875 | 0.88 | ALDH1A1 (0.41) | HSD17B10ALDH1A1KDM4ETDP1CHRNB2 | |
| SCHEMBL19019870 | 0.88 | CHRNB2 (0.43) | HSD17B10ALDH1A1KDM4ETDP1CHRNB2 | |
| SCHEMBL19061954 | 0.87 | HSD17B10 (0.42) | HSD17B10ALDH1A1KDM4ETDP1CHRNB2 | |
| SCHEMBL19061872 | 0.87 | MAPK1 (0.41) | ALDH1A1TDP1MAPK1MAPTL3MBTL1 | |
| SCHEMBL19061887 | 0.86 | L3MBTL1 (0.51) | HSD17B10CHRNB2CHRNA4KMT2AMEN1 | |
| SCHEMBL19019834 | 0.86 | PLA2G7 (0.47) | HSD17B10ALDH1A1CHRNB2CHRNA4KMT2A | |
| SCHEMBL19019922 | 0.85 | MAPK1 (0.50) | HSD17B10ALDH1A1KDM4ETDP1CHRNB2 | |
| SCHEMBL19061952 | 0.85 | CYP1A2 (0.51) | HSD17B10KDM4ECHRNB2CHRNA4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3184514-A1 | AUTOPHAGY INHIBITORS | Deutsches Krebsforschungszentrum (DE) | 2017-06-28 | — | — | EP | disclosed |