Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | UBE2M | P61081 | 3/20 | 0.44 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19019919 | 0.90 | HIF1A (0.47) | KDM4EPOLBCYP3A4HSD17B10PKM | |
| SCHEMBL19061459 | 0.86 | RAB9A (0.46) | KDM4EPOLBGRIN2BGRIN1RAB9A | |
| SCHEMBL19061885 | 0.84 | MEN1 (0.52) | KDM4ECYP3A4GRIN2BGRIN1ALDH1A1 | |
| SCHEMBL19019917 | 0.84 | TDP1 (0.46) | KDM4EPOLBCYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL19061887 | 0.84 | L3MBTL1 (0.51) | GRIN2BGRIN1RAB9ADAOHSD17B10 | |
| SCHEMBL19019922 | 0.84 | MAPK1 (0.50) | KDM4EPOLBRAB9AALDH1A1GAA | |
| SCHEMBL19062037 | 0.83 | METAP2 (0.43) | KDM4EGRIN2BGRIN1ALDH1A1GFER | |
| SCHEMBL19061954 | 0.83 | HSD17B10 (0.42) | KDM4EPOLBCYP3A4GRIN2BGRIN1 | |
| SCHEMBL19019870 | 0.82 | CHRNB2 (0.43) | KDM4EPOLBCYP3A4GRIN2BGRIN1 | |
| SCHEMBL19061730 | 0.82 | KDM4E (0.41) | KDM4EPOLBCYP3A4ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3184514-A1 | AUTOPHAGY INHIBITORS | Deutsches Krebsforschungszentrum (DE) | 2017-06-28 | — | — | EP | disclosed |