Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19062035 | 0.89 | HSD17B10 (0.40) | ALDH1A1KDM4ETDP1POLBMAPK1 | |
| SCHEMBL19061452 | 0.87 | PKM (0.48) | POLBMAPK1CHRNB2CHRNA4SMN1; SMN2 | |
| SCHEMBL19061884 | 0.87 | KMT2A (0.49) | ALDH1A1KDM4EPOLBNPC1RAB9A | |
| SCHEMBL19061730 | 0.86 | KDM4E (0.41) | ALDH1A1KDM4ETDP1POLBMAPK1 | |
| SCHEMBL19019922 | 0.86 | MAPK1 (0.50) | ALDH1A1KDM4ETDP1POLBRAB9A | |
| SCHEMBL19062036 | 0.85 | POLB (0.44) | KDM4EPOLBMAPK1CHRNB2CHRNA4 | |
| SCHEMBL19061889 | 0.85 | PKM (0.46) | ALDH1A1KDM4EPOLBMAPK1CHRNB2 | |
| SCHEMBL19061731 | 0.85 | POLB (0.40) | ALDH1A1KDM4ETDP1POLBMAPK1 | |
| SCHEMBL19019870 | 0.84 | CHRNB2 (0.43) | ALDH1A1KDM4ETDP1POLBNPC1 | |
| SCHEMBL19062037 | 0.84 | METAP2 (0.43) | ALDH1A1KDM4ETDP1MAPK1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3184514-A1 | AUTOPHAGY INHIBITORS | Deutsches Krebsforschungszentrum (DE) | 2017-06-28 | — | — | EP | disclosed |