Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | PIEZO1 | Q92508 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19061593 | 0.86 | ALDH1A1 (0.46) | KDM4EALDH1A1POLBMAPK1TDP1 | |
| SCHEMBL19061731 | 0.86 | POLB (0.40) | KDM4EALDH1A1POLBMAPK1TDP1 | |
| SCHEMBL19061452 | 0.84 | PKM (0.48) | POLBMAPK1CHRNB2CHRNA4HSD17B10 | |
| SCHEMBL19061884 | 0.84 | KMT2A (0.49) | KDM4EALDH1A1POLBMAPK1CHRNB2 | |
| SCHEMBL19019922 | 0.84 | MAPK1 (0.50) | KDM4EALDH1A1POLBMAPK1TDP1 | |
| SCHEMBL19019919 | 0.83 | HIF1A (0.47) | KDM4EPOLBMAPK1CHRNB2CHRNA4 | |
| SCHEMBL19061889 | 0.82 | PKM (0.46) | KDM4EALDH1A1ATMPOLBMAPK1 | |
| SCHEMBL19062036 | 0.82 | POLB (0.44) | KDM4EPOLBMAPK1CHRNB2CHRNA4 | |
| SCHEMBL19061599 | 0.82 | KDM4E (0.53) | KDM4EALDH1A1POLBHSD17B10PKM | |
| SCHEMBL19019870 | 0.80 | CHRNB2 (0.43) | KDM4EALDH1A1POLBMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3184514-A1 | AUTOPHAGY INHIBITORS | Deutsches Krebsforschungszentrum (DE) | 2017-06-28 | — | — | EP | disclosed |