Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19061597 | 0.89 | KDM4E (0.41) | KMT2ALMNAMAPK1POLBALDH1A1 | |
| SCHEMBL19061593 | 0.87 | ALDH1A1 (0.46) | KMT2AMAPK1POLBNPC1RAB9A | |
| SCHEMBL19061452 | 0.87 | PKM (0.48) | KMT2AMAPK1POLBSMN1; SMN2DRD2 | |
| SCHEMBL19019922 | 0.86 | MAPK1 (0.50) | KMT2AMAPK1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL19061889 | 0.85 | PKM (0.46) | KMT2AMAPK1POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL19062036 | 0.85 | POLB (0.44) | KMT2AMAPK1POLBSMN1; SMN2DRD2 | |
| SCHEMBL19019834 | 0.84 | PLA2G7 (0.47) | KMT2AMAPK1POLBNPC1RAB9A | |
| SCHEMBL19061730 | 0.84 | KDM4E (0.41) | KMT2AMAPK1POLBALDH1A1CHRNB2 | |
| SCHEMBL19061952 | 0.84 | CYP1A2 (0.51) | KMT2AMAPK1SMN1; SMN2DRD2DRD4 | |
| SCHEMBL22263137 | 0.84 | MAPK1 (0.50) | KMT2ALMNAMAPK1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3184514-A1 | AUTOPHAGY INHIBITORS | Deutsches Krebsforschungszentrum (DE) | 2017-06-28 | — | — | EP | disclosed |