Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19061887 | 0.88 | L3MBTL1 (0.51) | KMT2AMEN1MAPK1HSD17B10CHRNB2 | |
| SCHEMBL19019834 | 0.88 | PLA2G7 (0.47) | CYP1A2CYP2D6KMT2AMEN1MAPK1 | |
| SCHEMBL19019922 | 0.85 | MAPK1 (0.50) | OPRK1KMT2AMEN1MAPK1HSD17B10 | |
| SCHEMBL19062037 | 0.85 | METAP2 (0.43) | KMT2AMEN1MAPK1HSD17B10CHRNB2 | |
| SCHEMBL19061885 | 0.84 | MEN1 (0.52) | CYP1A2OPRK1KMT2AMEN1MAPK1 | |
| SCHEMBL19061884 | 0.84 | KMT2A (0.49) | KMT2AMEN1MAPK1HSD17B10CHRNB2 | |
| SCHEMBL19019917 | 0.84 | TDP1 (0.46) | CYP1A2CYP2D6OPRK1KMT2AMEN1 | |
| SCHEMBL19061459 | 0.84 | RAB9A (0.46) | KMT2AMEN1MAPK1HSD17B10CHRNB2 | |
| SCHEMBL19019870 | 0.84 | CHRNB2 (0.43) | KMT2AMEN1MAPK1HSD17B10CHRNB2 | |
| SCHEMBL14286352 | 0.84 | OPRK1 (0.48) | CYP1A2CYP2D6OPRK1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3184514-A1 | AUTOPHAGY INHIBITORS | Deutsches Krebsforschungszentrum (DE) | 2017-06-28 | — | — | EP | disclosed |