Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | TERF2 | Q15554 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19088918 | 0.92 | PDE4D (0.34) | PDE4DTAS1R3TAS1R1TAS1R2CTSK | |
| SCHEMBL19088927 | 0.91 | TAS1R3 (0.33) | PDE4DTAS1R3TAS1R1TAS1R2PDE10A | |
| SCHEMBL19084253 | 0.89 | TAS1R3 (0.35) | TAS1R3TAS1R1TAS1R2PDE10A | |
| SCHEMBL19089231 | 0.89 | PDE4D (0.34) | PDE4DIRAK4 | |
| SCHEMBL17898767 | 0.88 | PDE4D (0.33) | PDE4DTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL17427115 | 0.87 | PDE4D (0.34) | PDE4DTAS1R3TAS1R1TAS1R2CTSK | |
| SCHEMBL19088921 | 0.87 | RIPK1 (0.36) | PDE4DTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL19091508 | 0.87 | PDE4D (0.33) | PDE4DTAS1R3TAS1R1TAS1R2CTSK | |
| SCHEMBL19089225 | 0.86 | PDE4D (0.33) | PDE4D | |
| SCHEMBL17898692 | 0.86 | HPGDS (0.30) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017116949-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2017-07-06 | — | — | WO | disclosed |