Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 7/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8260665 | 0.88 | FAAH (0.38) | BRD4TDP1ACHEERN1FAAH | |
| SCHEMBL20663472 | 0.88 | FAAH (0.38) | BRD4TDP1ACHEERN1FAAH | |
| SCHEMBL19414915 | 0.87 | TDP1 (0.36) | BRD4TDP1ACHEERN1FAAH | |
| SCHEMBL22878134 | 0.84 | DDAH1 (0.39) | BRD4ACHEEPHX1ERN1ALDH1A1 | |
| SCHEMBL16093518 | 0.84 | MEN1 (0.42) | BRD4TDP1ACHEERN1FAAH | |
| SCHEMBL19130731 | 0.82 | SIRT1 (0.41) | ACHEEPHX1ALOX15TGM2 | |
| SCHEMBL13523926 | 0.81 | MEN1 (0.50) | TDP1MAPT | |
| SCHEMBL14930702 | 0.81 | KDM4E (0.44) | TDP1TGM2ALDH1A1MAPT | |
| SCHEMBL3676772 | 0.81 | TGM2 (0.46) | ACHEEPHX1ERN1TGM2 | |
| SCHEMBL12737518 | 0.79 | ACHE (0.42) | ACHETGM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170204138-A1 | ANTIBACTERIAL AGENTS | THE UNIVERSITY OF QUEENSLAND (AU) | 2017-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170204138-A1 | ANTIBACTERIAL AGENTS | VNN1, ASNS, AAAS | BRD4 3232/4885TDP1 4651/4885ACHE 4111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.