Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | UBE2M | P61081 | 1/20 | 0.44 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19157407 | 0.87 | HTR1A (0.56) | RORCNPC1RAB9AHTR1AHTR1D | |
| SCHEMBL19157902 | 0.86 | RORC (0.51) | RORCHTR1AHTR1DHTR1BADRB2 | |
| SCHEMBL15276826 | 0.80 | MEN1 (0.66) | NPC1L3MBTL1MAPTKMT2A | |
| SCHEMBL20083987 | 0.80 | RORC (0.57) | RORCRAB9AL3MBTL1MAPT | |
| SCHEMBL21844836 | 0.76 | ACKR3 (0.51) | HTR1AHTR1DHTR1BKCNH2KMT2A | |
| SCHEMBL20083988 | 0.75 | RORC (0.48) | RORCRAB9AL3MBTL1MAPTHTR1A | |
| SCHEMBL20083898 | 0.75 | KDR (0.44) | HTR1AHTR1DHTR1BKCNH2KMT2A | |
| SCHEMBL21844945 | 0.75 | ACKR3 (0.53) | NPC1RAB9AMAPTUBE2MDCUN1D1 | |
| SCHEMBL19157150 | 0.73 | PARP1 (0.51) | NPC1RAB9AL3MBTL1MAPTTP53 | |
| SCHEMBL15276938 | 0.73 | MEN1 (0.54) | NPC1RAB9AL3MBTL1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794565-B1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS INC (US) | 2017-07-26 | — | — | EP | disclosed |