Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20083988 | 0.90 | RORC (0.48) | RORCPOLBSMN1; SMN2GAAHTT | |
| SCHEMBL19157407 | 0.85 | HTR1A (0.56) | RORCRAB9AACKR3FAAH | |
| SCHEMBL19157902 | 0.82 | RORC (0.51) | RORCACKR3 | |
| SCHEMBL19157247 | 0.80 | RORC (0.49) | RORCRAB9AL3MBTL1MAPT | |
| SCHEMBL15276820 | 0.78 | SIRT2 (0.73) | SMN1; SMN2GAAHTTRAB9ASIRT2 | |
| SCHEMBL19157242 | 0.75 | RAB9A (0.62) | RORCPOLBSMN1; SMN2GAAHTT | |
| SCHEMBL15276790 | 0.74 | SIRT2 (0.72) | POLBSMN1; SMN2GAAHTTRAB9A | |
| SCHEMBL19157278 | 0.73 | KDM4E (0.69) | RORCPOLBSMN1; SMN2GAAHTT | |
| SCHEMBL21844943 | 0.72 | ALDH1A1 (0.54) | POLBSMN1; SMN2RAB9AL3MBTL1ACKR3 | |
| SCHEMBL21844944 | 0.72 | HTR1A (0.54) | POLBSMN1; SMN2HTTRAB9AACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312160-A1 | HEPATITIS B ANTIVIRAL AGENTS | Novira Therapeutics Inc. (US) | 2018-04-25 | — | — | EP | disclosed |