Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | PTPRB | P23467 | 1/20 | 0.31 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.30 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17917765 | 0.74 | ALDH1A1 (0.35) | KDM4EL3MBTL1HPGDTSHRCYP3A4 | |
| SCHEMBL13921765 | 0.68 | NOS3 (0.48) | AGBL2KDM4ENOS3NOS1NOS2 | |
| SCHEMBL22672488 | 0.68 | SLC13A5 (0.39) | AGBL2KDM4E | |
| SCHEMBL6984523 | 0.65 | L3MBTL1 (0.42) | KDM4EL3MBTL1NOS3NOS1NOS2 | |
| SCHEMBL25680841 | 0.63 | NPSR1 (0.44) | KDM4ESETDB1 | |
| SCHEMBL3387105 | 0.62 | SETDB1 (0.47) | L3MBTL1SETDB1 | |
| SCHEMBL21031175 | 0.62 | ALDH1A1 (0.40) | KDM4EL3MBTL1SSTR4CYP3A4 | |
| SCHEMBL20483300 | 0.62 | ADORA2A (0.46) | AGBL2NOS3NOS1NOS2 | |
| SCHEMBL17315813 | 0.62 | GRIN2B (0.39) | NOS3NOS1NOS2 | |
| SCHEMBL12169342 | 0.62 | NOS3 (0.50) | KDM4ENOS3NOS1NOS2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170217931-A1 | COMPOUNDS FOR USE IN ANTHELMINTHIC TREATMENT | BAYER ANIMAL HEALTH GMBH (DE) | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217931-A1 | COMPOUNDS FOR USE IN ANTHELMINTHIC TREATMENT | ACHE, COX5B, TUBB6 | AGBL2 2200/4885KDM4E 2155/4885L3MBTL1 2180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.