Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19196315 | 0.89 | MAOB (0.45) | MAOBMAOAMEN1KMT2AMIF | |
| SCHEMBL19196064 | 0.86 | MIF (0.45) | MAOBMAOACA9CA12CA1 | |
| SCHEMBL17525313 | 0.84 | ALDH1A1 (0.55) | MAOBMEN1KMT2ATP53MAPT | |
| SCHEMBL19196346 | 0.84 | MAOB (0.41) | MAOBMAOACA9CA12CA2 | |
| SCHEMBL19196312 | 0.80 | MAPT (0.49) | MAOBMAOAMEN1KMT2AMIF | |
| SCHEMBL19196313 | 0.77 | MAPT (0.58) | MAOBMAOAMEN1KMT2AMAPT | |
| SCHEMBL17037974 | 0.76 | HSD11B1 (0.47) | MAOBMAOACA9CA12CA1 | |
| SCHEMBL19203422 | 0.75 | MEN1 (0.51) | MAOBMAOAMEN1KMT2ATP53 | |
| SCHEMBL17525293 | 0.69 | MAPT (0.61) | MAOBMEN1KMT2ATP53MAPT | |
| SCHEMBL10305750 | 0.69 | CA12 (0.77) | MAOBMAOACA9CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10921327-B2 | Probes for quantitative imaging of thiols in various environments | BAYLOR COLLEGE OF MEDICINE (US) | 2021-02-16 | — | — | US | disclosed |
| US-20170219599-A1 | PROBES FOR QUANTITATIVE IMAGING OF THIOLS IN VARIOUS ENVIRONMENTS | BAYLOR COLLEGE OF MEDICINE (US) | 2017-08-03 | — | — | US | disclosed |
| US-20170219599-A1 | PROBES FOR QUANTITATIVE IMAGING OF THIOLS IN VARIOUS ENVIRONMENTS | BAYLOR COLLEGE OF MEDICINE (US) | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10921327-B2 | Probes for quantitative imaging of thiols in various environments | SQOR, TXN2, TXNRD1 | MAOB 1766/4885MAOA 1957/4885CA9 2410/4885 |
| US-20170219599-A1 | PROBES FOR QUANTITATIVE IMAGING OF THIOLS IN VARIOUS ENVIRONMENTS | SQOR, TXN2, TXNRD1 | MAOB 1766/4885MAOA 1957/4885CA9 2410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.