Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.45 |
| ▸ | MAOA | P21397 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | P4HB | P07237 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19196314 | 0.89 | MAOB (0.42) | MAOBMAOAALDH1A1NPC1MAPT | |
| SCHEMBL19196346 | 0.87 | MAOB (0.41) | MAOBMAOAKDM4EALDH1A1HPGD | |
| SCHEMBL19203422 | 0.85 | MEN1 (0.51) | MAOBMAOAKDM4EALDH1A1HPGD | |
| SCHEMBL19196064 | 0.77 | MIF (0.45) | MAOBMAOAALDH1A1HPGDMAPT | |
| SCHEMBL19196312 | 0.75 | MAPT (0.49) | MAOBMAOAKDM4EALDH1A1HPGD | |
| SCHEMBL19196313 | 0.75 | MAPT (0.58) | MAOBMAOAKDM4EALDH1A1NPC1 | |
| SCHEMBL17525296 | 0.75 | MAOB (0.50) | MAOBMAOAKDM4EALDH1A1HPGD | |
| SCHEMBL17525313 | 0.74 | ALDH1A1 (0.55) | MAOBKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL17037974 | 0.73 | HSD11B1 (0.47) | MAOBMAOAKDM4EALDH1A1HPGD | |
| SCHEMBL15984324 | 0.67 | MEN1 (0.57) | KDM4EALDH1A1HPGDNPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170219599-A1 | PROBES FOR QUANTITATIVE IMAGING OF THIOLS IN VARIOUS ENVIRONMENTS | BAYLOR COLLEGE OF MEDICINE (US) | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170219599-A1 | PROBES FOR QUANTITATIVE IMAGING OF THIOLS IN VARIOUS ENVIRONMENTS | SQOR, TXN2, TXNRD1 | MAOB 1766/4885MAOA 1957/4885KDM4E 3799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.